# G protein-coupled receptor kinase 5

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21154919](https://www.wikidata.org/wiki/Q21154919)  
**Source**: https://4ort.xyz/entity/g-protein-coupled-receptor-kinase-5-q21154919


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P34947)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947)
5. [G-protein-coupled receptor kinase 5 phosphorylates p53 and inhibits DNA damage-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947)
6. [The G-protein-coupled receptor kinase 5 inhibits NFkappaB transcriptional activity by inducing nuclear accumulation of IkappaB alpha](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947)
7. [Beta-arrestin1 phosphorylation by GRK5 regulates G protein-independent 5-HT4 receptor signalling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947)
8. [Characterization of G-protein coupled receptor kinase interaction with the neurokinin-1 receptor using bioluminescence resonance energy transfer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947)
9. [Structure-function analysis of G protein-coupled receptor kinase-5. Role of the carboxyl terminus in kinase regulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947)
10. [Role for the regulator of G-protein signaling homology domain of G protein-coupled receptor kinases 5 and 6 in beta 2-adrenergic receptor and rhodopsin phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947)
11. [A predicted amphipathic helix mediates plasma membrane localization of GRK5](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947)
12. [Cloning and expression of GRK5: a member of the G protein-coupled receptor kinase family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947)
13. [Involvement of G protein-coupled receptor kinase 5 in homologous desensitization of the thyrotropin receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947)
14. [G-Protein Coupled Receptor Kinase 5 Regulates Prostate Tumor Growth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947)
15. [Expression, purification, and characterization of the G protein-coupled receptor kinase GRK5](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947)
16. Ensembl Release 99
17. UMLS 2023