# FYN proto-oncogene, Src family tyrosine kinase

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28559536](https://www.wikidata.org/wiki/Q28559536)  
**Source**: https://4ort.xyz/entity/fyn-proto-oncogene-src-family-tyrosine-kinase-q28559536


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q62844)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62844)
5. [Role of NFAT and AP-1 in PGE2-mediated T cell suppression in burn injury](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62844)
6. [Fyn-mediated phosphorylation of NR2B Tyr-1336 controls calpain-mediated NR2B cleavage in neurons and heterologous systems](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62844)
7. [Characterization and location of Src-dependent tyrosine phosphorylation in rat brain mitochondria](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62844)
8. [Phosphorylation of c-Cbl protooncogene product following ethanol administration in rat cerebellum: possible involvement of Fyn kinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62844)
9. [Thy-1 molecule associates with protein tyrosine kinase(s) in rat mesangial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62844)
10. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62844)
11. [Association of Src-like protein tyrosine kinases with the CD2 cell surface molecule in rat T lymphocytes and natural killer cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62844)
12. [Opioid addiction and pregnancy: perinatal exposure to buprenorphine affects myelination in the developing brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62844)
13. [Physical association of the cytoplasmic domain of CD2 with the tyrosine kinases p56lck and p59fyn](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62844)
14. [Identification of a novel protein complex containing annexin VI, Fyn, Pyk2, and the p120(GAP) C2 domain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62844)
15. [NMDA receptor function is regulated by the inhibitory scaffolding protein, RACK1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62844)
16. [Metabotropic glutamate receptor 5 is a coreceptor for Alzheimer aβ oligomer bound to cellular prion protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62844)
17. [Molecular associations between the T-lymphocyte antigen receptor complex and the surface antigens CD2, CD4, or CD8 and CD5](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62844)
18. [Prolactin induced tyrosine phosphorylation of p59fyn may mediate phosphatidylinositol 3-kinase activation in Nb2 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62844)
19. [Tyrosine kinase and tyrosine phosphatase participate in regulation of interactions of NMDA receptor subunit 2A with Src and Fyn mediated by PSD-95 after transient brain ischemia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62844)
20. [The protein tyrosine kinase P59fyn is associated with prolactin (PRL) receptor and is activated by PRL stimulation of T-lymphocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62844)
21. [Tyrosine kinase FYN negatively regulates NOX4 in cardiac remodeling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62844)
22. [Kainate-induced seizures alter protein composition and N-methyl-D-aspartate receptor function of rat forebrain postsynaptic densities](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62844)
23. [Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62844)
24. [Phosphatidylinositol 3-kinase interacts with the adaptor protein Dab1 in response to Reelin signaling and is required for normal cortical lamination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62844)
25. [CSK: a protein-tyrosine kinase involved in regulation of src family kinases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62844)
26. [PSD-95 stabilizes NMDA receptors by inducing the degradation of STEP61.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62844)
27. [Netrin-1 mediates neuronal survival through PIKE-L interaction with the dependence receptor UNC5B](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62844)
28. [Scaffolding of Fyn kinase to the NMDA receptor determines brain region sensitivity to ethanol](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62844)
29. [TGF-beta abrogates TCR-mediated signaling by upregulating tyrosine phosphatases in T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62844)
30. ensembl Release 106