# FURIN

> protein-coding gene in the species Homo sapiens

**Wikidata**: [Q14916427](https://www.wikidata.org/wiki/Q14916427)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Furin)  
**Source**: https://4ort.xyz/entity/furin


## References

1. Ensembl Release 99
2. Ensembl Release 87
3. Q20641742
4. Online Mendelian Inheritance in Man
5. [Proprotein convertase furin interacts with and cleaves pro-ADAMTS4 (Aggrecanase-1) in the trans-Golgi network](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P09958)
6. [GOA](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P09958)
7. [Processing of Prothyrotropin-releasing Hormone by the Family of Prohormone Convertases](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P09958)
8. [The shedding activity of ADAM17 is sequestered in lipid rafts](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P09958)
9. [The ordered and compartment-specfific autoproteolytic removal of the furin intramolecular chaperone is required for enzyme activation](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P09958)
10. [Activation of the furin endoprotease is a multiple-step process: requirements for acidification and internal propeptide cleavage](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P09958)
11. [Cellular processing of the nerve growth factor precursor by the mammalian pro-protein convertases](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P09958)
12. [The prosegments of furin and PC7 as potent inhibitors of proprotein convertases. In vitro and ex vivo assessment of their efficacy and selectivity](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P09958)
13. [Latent myostatin has significant activity and this activity is controlled more efficiently by WFIKKN1 than by WFIKKN2](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P09958)
14. [K153R polymorphism in myostatin gene increases the rate of promyostatin activation by furin](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P09958)
15. [Furin mediates enhanced production of fibrillogenic ABri peptides in familial British dementia](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P09958)
16. [Beta-amyloid protein converting enzyme 1 and brain-specific type II membrane protein BRI3: binding partners processed by furin](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P09958)
17. [Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P09958)
18. [Furin-mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasis](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P09958)
19. [Identification of the paired basic convertases implicated in HIV gp160 processing based on in vitro assays and expression in CD4(+) cell lines](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P09958)
20. [Cell-surface processing of pro-ADAMTS9 by furin](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P09958)
21. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P09958)
22. [Cargo-selective endosomal sorting for retrieval to the Golgi requires retromer](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P09958)
23. [Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P09958)
24. [The proprotein convertase (PC) PCSK9 is inactivated by furin and/or PC5/6A: functional consequences of natural mutations and post-translational modifications](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P09958)
25. [Human carcinoma cell growth and invasiveness is impaired by the propeptide of the ubiquitous proprotein convertase furin](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P09958)
26. [Differential processing of proenkephalin by prohormone convertases 1(3) and 2 and furin](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P09958)
27. HomoloGene build68
28. [Orthologous MAtrix](https://omabrowser.org/oma/vps/P09958/)
29. UniProt
30. [Identifiers.org](http://www.ebi.ac.uk/miriam/main/collections/MIR:00000069)
31. UMLS 2023
32. [Bgee](https://www.bgee.org/gene/ENSG00000140564)
33. [OpenAlex](https://docs.openalex.org/download-snapshot/snapshot-data-format)