# Frizzled class receptor 8

> mammalian protein found in Mus musculus

**Wikidata**: [Q21981588](https://www.wikidata.org/wiki/Q21981588)  
**Source**: https://4ort.xyz/entity/frizzled-class-receptor-8-q21981588


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q61091)
3. Q20641742
4. [Mammalian Ryk Is a Wnt Coreceptor Required for Stimulation of Neurite Outgrowth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091)
5. [Identification of a PDZ Domain Containing Golgi Protein, GOPC, as an Interaction Partner of Frizzled](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091)
6. [Mouse Cristin/R-spondin Family Proteins Are Novel Ligands for the Frizzled 8 and LRP6 Receptors and Activate β-Catenin-dependent Gene Expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091)
7. [ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091)
8. [LDL-receptor-related proteins in Wnt signal transduction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091)
9. [Structural Studies of Wnts and Identification of an LRP6 Binding Site](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091)
10. [Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091)
11. [SOST Is a Ligand for LRP5/LRP6 and a Wnt Signaling Inhibitor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091)
12. [IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091)
13. [Structural Basis of Wnt Recognition by Frizzled](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61091&geneProductId=UniProtKB:Q61091)
14. [Reconstitution of a Frizzled8·Wnt3a·LRP6 Signaling Complex Reveals Multiple Wnt and Dkk1 Binding Sites on LRP6](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61091&geneProductId=UniProtKB:Q61091)
15. [LDL-receptor-related protein 6 is a receptor for Dickkopf proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61091&geneProductId=UniProtKB:Q61091)
16. [Mammalian Ryk Is a Wnt Coreceptor Required for Stimulation of Neurite Outgrowth](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61091&geneProductId=UniProtKB:Q61091)
17. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61091&geneProductId=UniProtKB:Q61091)
18. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091)
19. [Reconstitution of a Frizzled8·Wnt3a·LRP6 Signaling Complex Reveals Multiple Wnt and Dkk1 Binding Sites on LRP6](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091)
20. [LDL-receptor-related protein 6 is a receptor for Dickkopf proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091)
21. [Structural Basis of Wnt Recognition by Frizzled](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091)
22. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091)
23. [Vascular Development in the Retina and Inner Ear](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61091&geneProductId=UniProtKB:Q61091)
24. [Vascular Development in the Retina and Inner Ear](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091)
25. [Wnt signaling is required for thymocyte development and activates Tcf-1 mediated transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091)
26. [MAGI-3 is involved in the regulation of the JNK signaling pathway as a scaffold protein for frizzled and Ltap](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091)
27. [Wnt/β-catenin signaling is required for CNS, but not non-CNS, angiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091)
28. [Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091)
29. [Wnt Proteins Induce Dishevelled Phosphorylation via an LRP5/6- Independent Mechanism, Irrespective of Their Ability To Stabilize β-Catenin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091)
30. [Wnt Proteins Induce Dishevelled Phosphorylation via an LRP5/6- Independent Mechanism, Irrespective of Their Ability To Stabilize β-Catenin](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61091&geneProductId=UniProtKB:Q61091)
31. [Truncated mutants of the putative Wnt receptor LRP6/Arrow can stabilize β-catenin independently of Frizzled proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61091&geneProductId=UniProtKB:Q61091)
32. [Wnt signaling is required for thymocyte development and activates Tcf-1 mediated transcription](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61091&geneProductId=UniProtKB:Q61091)
33. [Analysis of combinatorial effects of Wnts and Frizzleds on β‐catenin/armadillo stabilization and Dishevelled phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61091&geneProductId=UniProtKB:Q61091)
34. [Mouse Cristin/R-spondin Family Proteins Are Novel Ligands for the Frizzled 8 and LRP6 Receptors and Activate β-Catenin-dependent Gene Expression](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61091&geneProductId=UniProtKB:Q61091)
35. [Truncated mutants of the putative Wnt receptor LRP6/Arrow can stabilize β-catenin independently of Frizzled proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091)
36. [Analysis of combinatorial effects of Wnts and Frizzleds on β‐catenin/armadillo stabilization and Dishevelled phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091)
37. ensembl Release 106