# Frizzled class receptor 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q21983260](https://www.wikidata.org/wiki/Q21983260)  
**Source**: https://4ort.xyz/entity/frizzled-class-receptor-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O70421)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70421)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O70421&geneProductId=UniProtKB:O70421)
6. [Wnt7b activates canonical signaling in epithelial and vascular smooth muscle cells through interactions with Fzd1, Fzd10, and LRP5.](http://www.ebi.ac.uk/QuickGO/annotations?protein=O70421&geneProductId=UniProtKB:O70421)
7. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70421)
8. [Wnt7b activates canonical signaling in epithelial and vascular smooth muscle cells through interactions with Fzd1, Fzd10, and LRP5.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70421)
9. [Wnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-catenin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70421)
10. [The stomach mesenchymal transcription factor Barx1 specifies gastric epithelial identity through inhibition of transient Wnt signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70421)
11. [Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: general implications for tissue fusion processes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70421)
12. [Murine Frizzled-1 behaves as an antagonist of the canonical Wnt/beta-catenin signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70421)
13. [Wnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-catenin](http://www.ebi.ac.uk/QuickGO/annotations?protein=O70421&geneProductId=UniProtKB:O70421)
14. [The Wnt/beta-catenin pathway regulates Gli-mediated Myf5 expression during somitogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70421)
15. [A Wnt1 regulated Frizzled-1/β-Catenin signaling pathway as a candidate regulatory circuit controlling mesencephalic dopaminergic neuron-astrocyte crosstalk: Therapeutical relevance for neuron survival and neuroprotection](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70421)
16. [Role of the Wnt receptor Frizzled-1 in presynaptic differentiation and function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70421)
17. ensembl Release 106