# Frizzled class receptor 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21204094](https://www.wikidata.org/wiki/Q21204094)  
**Source**: https://4ort.xyz/entity/frizzled-class-receptor-1-q21204094


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9UP38)
3. Q20641742
4. [Sequence requirement and subtype specificity in the high‐affinity interaction between human frizzled and dishevelled proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP38)
5. [Myocilin Is a Modulator of Wnt Signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP38)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UP38&geneProductId=UniProtKB:Q9UP38)
7. [Uncovering novel actors in astrocyte–neuron crosstalk in P arkinson's disease: the W nt/β‐catenin signaling cascade as the common final pathway for neuroprotection and self‐repair](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UP38&geneProductId=UniProtKB:Q9UP38)
8. [Human frizzled 1 interacts with transforming Wnts to transduce a TCF dependent transcriptional response](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UP38&geneProductId=UniProtKB:Q9UP38)
9. [Secreted Frizzled-related protein-1 is a negative regulator of androgen receptor activity in prostate cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP38)
10. [Dysfunction of Wnt signaling and synaptic disassembly in neurodegenerative diseases](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UP38&geneProductId=UniProtKB:Q9UP38)
11. [Mapping of Wnt‐Frizzled interactions by multiplex CRISPR targeting of receptor gene families](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UP38&geneProductId=UniProtKB:Q9UP38)
12. [The Low Density Lipoprotein Receptor-1, LRP1, Interacts with the Human Frizzled-1 (HFz1) and Down-regulates the Canonical Wnt Signaling Pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP38)
13. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP38)
14. [Uncovering novel actors in astrocyte–neuron crosstalk in P arkinson's disease: the W nt/β‐catenin signaling cascade as the common final pathway for neuroprotection and self‐repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP38)
15. [Human frizzled 1 interacts with transforming Wnts to transduce a TCF dependent transcriptional response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP38)
16. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP38)
17. [Dysfunction of Wnt signaling and synaptic disassembly in neurodegenerative diseases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP38)
18. [Mapping of Wnt‐Frizzled interactions by multiplex CRISPR targeting of receptor gene families](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP38)
19. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UP38&geneProductId=UniProtKB:Q9UP38)
20. [A Coated Vesicle-associated Kinase of 104 kDa (CVAK104) Induces Lysosomal Degradation of Frizzled 5 (Fzd5)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP38)
21. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP38)
22. [Stably overexpressed human Frizzled-2 signals through the β-catenin pathway and does not activate Ca2+-mobilization in Human Embryonic Kidney 293 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP38)
23. [Wnt3‐frizzled 1 chimera as a model to study canonical Wnt signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP38)
24. [Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UP38&geneProductId=UniProtKB:Q9UP38)
25. [The Low Density Lipoprotein Receptor-1, LRP1, Interacts with the Human Frizzled-1 (HFz1) and Down-regulates the Canonical Wnt Signaling Pathway](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UP38&geneProductId=UniProtKB:Q9UP38)
26. [Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP38)
27. Ensembl Release 99
28. Transporter Classification database