# frataxin

> mammalian protein found in Homo sapiens

**Wikidata**: [Q409999](https://www.wikidata.org/wiki/Q409999)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Frataxin)  
**Source**: https://4ort.xyz/entity/frataxin


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q16595)
3. Q20641742
4. Freebase Data Dumps. 2013
5. [Mitochondrial Hspa9/Mortalin regulates erythroid differentiation via iron-sulfur cluster assembly](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595)
6. [Frataxin interacts functionally with mitochondrial electron transport chain proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595)
7. [Frataxin-mediated iron delivery to ferrochelatase in the final step of heme biosynthesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595)
8. [Frataxin-mediated iron delivery to ferrochelatase in the final step of heme biosynthesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16595&geneProductId=UniProtKB:Q16595)
9. [Iron-sulfur cluster biosynthesis. Characterization of frataxin as an iron donor for assembly of [2Fe-2S] clusters in ISU-type proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16595&geneProductId=UniProtKB:Q16595)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595)
11. [N-terminal iron-mediated self-cleavage of human frataxin: regulation of iron binding and complex formation with target proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16595&geneProductId=UniProtKB:Q16595)
12. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16595&geneProductId=UniProtKB:Q16595)
13. [Dynamics, stability and iron-binding activity of frataxin clinical mutants](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16595&geneProductId=UniProtKB:Q16595)
14. [Assembly of human frataxin is a mechanism for detoxifying redox-active iron](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16595&geneProductId=UniProtKB:Q16595)
15. [Assembly of human frataxin is a mechanism for detoxifying redox-active iron](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595)
16. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595)
17. [Iron-sulfur cluster biosynthesis. Characterization of frataxin as an iron donor for assembly of [2Fe-2S] clusters in ISU-type proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595)
18. [N-terminal iron-mediated self-cleavage of human frataxin: regulation of iron binding and complex formation with target proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595)
19. [Dynamics, stability and iron-binding activity of frataxin clinical mutants](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595)
20. [In vivo maturation of human frataxin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595)
21. [In vivo maturation of human frataxin](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16595&geneProductId=UniProtKB:Q16595)
22. [Iron Sulfur and Molybdenum Cofactor Enzymes Regulate the Drosophila Life Cycle by Controlling Cell Metabolism.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595)
23. [The effects of frataxin silencing in HeLa cells are rescued by the expression of human mitochondrial ferritin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595)
24. [Iron-dependent regulation of frataxin expression: implications for treatment of Friedreich ataxia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595)
25. [Iron-sulfur protein maturation in human cells: evidence for a function of frataxin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595)
26. [A pool of extramitochondrial frataxin that promotes cell survival](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595)
27. [The effects of frataxin silencing in HeLa cells are rescued by the expression of human mitochondrial ferritin](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16595&geneProductId=UniProtKB:Q16595)
28. [Molecular control of the cytosolic aconitase/IRP1 switch by extramitochondrial frataxin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595)
29. Ensembl Release 99
30. Identifiers.org
31. Quora
32. Transporter Classification database
33. [OpenAlex](https://docs.openalex.org/download-snapshot/snapshot-data-format)