# Fragile histidine triad diadenosine triphosphatase

> mammalian protein found in Homo sapiens

**Wikidata**: [Q22676739](https://www.wikidata.org/wiki/Q22676739)  
**Source**: https://4ort.xyz/entity/fragile-histidine-triad-diadenosine-triphosphatase


## References

1. UniProt
2. Q20641742
3. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49789)
4. [Fhit, a putative tumor suppressor in humans, is a dinucleoside 5',5"'-P1,P3-triphosphate hydrolase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49789)
5. [Structure-based analysis of catalysis and substrate definition in the HIT protein family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49789)
6. [The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49789)
7. [The tumor suppressor Fhit acts as a repressor of beta-catenin transcriptional activity.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49789)
8. [Synergistic tumor suppression by coexpression of FHIT and p53 coincides with FHIT-mediated MDM2 inactivation and p53 stabilization in human non-small cell lung cancer cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49789)
9. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49789)
10. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49789)
11. [Genetic, biochemical, and crystallographic characterization of Fhit-substrate complexes as the active signaling form of Fhit](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49789)
12. [MAD analysis of FHIT, a putative human tumor suppressor from the HIT protein family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49789)
13. [Pooled-matrix protein interaction screens using Barcode Fusion Genetics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49789)
14. [Fhit is a physiological target of the protein kinase Src](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49789)
15. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49789&geneProductId=UniProtKB:P49789)
16. Ensembl Release 99