# Fos proto-oncogene, AP-1 transcription factor subunit

> mammalian protein found in Homo sapiens

**Wikidata**: [Q2745522](https://www.wikidata.org/wiki/Q2745522)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Protein_c-Fos)  
**Source**: https://4ort.xyz/entity/fos-proto-oncogene-ap-1-transcription-factor-subunit


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P01100)
3. Q20641742
4. Freebase Data Dumps. 2013
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
6. [Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-β-induced transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
7. [GOA](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01100)
8. [Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-β-induced transcription](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01100)
9. [CHOP enhancement of gene transcription by interactions with Jun/Fos AP-1 complex proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
10. [Mutual regulation of c-Jun and ATF2 by transcriptional activation and subcellular localization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
11. [Transcriptional synergy mediated by SAF-1 and AP-1: critical role of N-terminal polyalanine and two zinc finger domains of SAF-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
12. [LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
13. [Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
14. [STAT-1 and c-Fos interaction in nitric oxide synthase-2 gene activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
15. [Thermodynamic analysis of Jun-Fos coiled coil peptide antagonists](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
16. [A human interactome in three quantitative dimensions organized by stoichiometries and abundances](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
17. [In situ proximity ligation detection of c-Jun/AP-1 dimers reveals increased levels of c-Jun/Fra1 complexes in aggressive breast cancer cell lines in vitro and in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
18. [Visualization of AP-1 NF-kappaB ternary complexes in living cells by using a BiFC-based FRET.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
19. [Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
20. [The protein interaction landscape of the human CMGC kinase group](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
21. [A Comprehensive Resource of Interacting Protein Regions for Refining Human Transcription Factor Networks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
22. [Tcl1 functions as a transcriptional regulator and is directly involved in the pathogenesis of CLL.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
23. [A human MAP kinase interactome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
24. [Crystal structure of the heterodimeric bZIP transcription factor c-Fos-c-Jun bound to DNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
25. [Protein kinase C α is a central signaling node and therapeutic target for breast cancer stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
26. [Identification of bZIP interaction partners of viral proteins HBZ, MEQ, BZLF1, and K-bZIP using coiled-coil arrays](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
27. [Ecotopic viral integration site 1 (EVI1) regulates multiple cellular processes important for cancer and is a synergistic partner for FOS protein in invasive tumors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
28. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
29. [Intrinsic structural disorder of the C-terminal activation domain from the bZIP transcription factor Fos](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
30. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
31. [Presenilin 1 suppresses the function of c-Jun homodimers via interaction with QM/Jif-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
32. [Platelet-Activating Factor Induction of Activator Protein-1 Signaling in Bronchial Epithelial Cells](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01100)
33. [Mitochondrial impairment increases FL-PINK1 levels by calcium-dependent gene expression](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01100)
34. [Platelet-Activating Factor Induction of Activator Protein-1 Signaling in Bronchial Epithelial Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
35. [Mitochondrial impairment increases FL-PINK1 levels by calcium-dependent gene expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
36. [Downregulation of Inflammatory MicroRNAs by Ig-like Transcript 3 Is Essential for the Differentiation of Human CD8+ T Suppressor Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
37. [Cadmium induces matrix metalloproteinase-9 expression via ROS-dependent EGFR, NF-кB, and AP-1 pathways in human endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
38. [Differential transcriptional regulation of the monocyte-chemoattractant protein-1 (MCP-1) gene in tumorigenic and non-tumorigenic HPV 18 positive cells: the role of the chromatin structure and AP-1 composition](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
39. [Reactive oxygen species mediates the apoptosis induced by transforming growth factor beta(2) in human lens epithelial cells](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01100)
40. [Role of DNA 5-methylcytosine transferase in cell transformation by fos](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
41. [CHOP enhancement of gene transcription by interactions with Jun/Fos AP-1 complex proteins](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01100)
42. [Reactive oxygen species mediates the apoptosis induced by transforming growth factor beta(2) in human lens epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01100)
43. Ensembl Release 99
44. [OpenAlex](https://docs.openalex.org/download-snapshot/snapshot-data-format)