# Forkhead box P3

> mammalian protein found in Homo sapiens

**Wikidata**: [Q426188](https://www.wikidata.org/wiki/Q426188)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/FOXP3)  
**Source**: https://4ort.xyz/entity/forkhead-box-p3


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9BZS1)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZS1)
5. [FOXP3 controls regulatory T cell function through cooperation with NFAT](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZS1)
6. [Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZS1)
7. [FOXP3 up-regulates p21 expression by site-specific inhibition of histone deacetylase 2/histone deacetylase 4 association to the locus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZS1)
8. [Foxp3 represses retroviral transcription by targeting both NF-kappaB and CREB pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZS1)
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BZS1&geneProductId=UniProtKB:Q9BZS1)
10. [Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZS1)
11. [PDCD5 negatively regulates autoimmunity by upregulating FOXP3+ regulatory T cells and suppressing Th17 and Th1 responses](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZS1)
12. [TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZS1)
13. [Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid arthritis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZS1)
14. [Activation of the aryl hydrocarbon receptor induces human type 1 regulatory T cell-like and Foxp3(+) regulatory T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZS1)
15. [Isoform-specific inhibition of ROR alpha-mediated transcriptional activation by human FOXP3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZS1)
16. [Cutting Edge: a novel, human-specific interacting protein couples FOXP3 to a chromatin-remodeling complex that contains KAP1/TRIM28](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZS1)
17. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZS1)
18. [Widespread macromolecular interaction perturbations in human genetic disorders](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZS1)
19. [The ubiquitin ligase Stub1 negatively modulates regulatory T cell suppressive activity by promoting degradation of the transcription factor Foxp3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZS1)
20. [FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZS1)
21. [Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZS1)
22. [Structure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZS1)
23. [Analysis of FOXP3 reveals multiple domains required for its function as a transcriptional repressor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZS1)
24. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BZS1&geneProductId=UniProtKB:Q9BZS1)
25. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZS1)
26. [FOXP3 ensembles in T-cell regulation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BZS1&geneProductId=UniProtKB:Q9BZS1)
27. [FOXP3 controls regulatory T cell function through cooperation with NFAT](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BZS1&geneProductId=UniProtKB:Q9BZS1)
28. [PDCD5 negatively regulates autoimmunity by upregulating FOXP3+ regulatory T cells and suppressing Th17 and Th1 responses](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BZS1&geneProductId=UniProtKB:Q9BZS1)
29. [Subcellular localization of FOXP3 in human regulatory and nonregulatory T cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BZS1&geneProductId=UniProtKB:Q9BZS1)
30. [Analysis of FOXP3 reveals multiple domains required for its function as a transcriptional repressor](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BZS1&geneProductId=UniProtKB:Q9BZS1)
31. [Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BZS1&geneProductId=UniProtKB:Q9BZS1)
32. [FOXP3 ensembles in T-cell regulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZS1)
33. [Subcellular localization of FOXP3 in human regulatory and nonregulatory T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZS1)
34. [Critical role of heme oxygenase-1 in Foxp3-mediated immune suppression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZS1)
35. [A novel function for FOXP3 in humans: intrinsic regulation of conventional T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZS1)
36. [Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZS1)
37. [T-bet, GATA-3, and Foxp3 expression and Th1/Th2 cytokine production in the clinical outcome of human infection with Leishmania (Viannia) species](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZS1)
38. Ensembl Release 99
39. Identifiers.org
40. [OpenAlex](https://docs.openalex.org/download-snapshot/snapshot-data-format)