# Forkhead box A2

> mammalian protein found in Mus musculus

**Wikidata**: [Q21983973](https://www.wikidata.org/wiki/Q21983973)  
**Source**: https://4ort.xyz/entity/forkhead-box-a2-q21983973


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P35583)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
5. [Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35583&geneProductId=UniProtKB:P35583)
6. [Genome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35583&geneProductId=UniProtKB:P35583)
7. [Identification and characterization of a 315-base pair enhancer, located more than 55 kilobases 5' of the apolipoprotein B gene, that confers expression in the intestine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35583&geneProductId=UniProtKB:P35583)
8. [Conserved transcriptional regulatory domains of the pdx-1 gene](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35583&geneProductId=UniProtKB:P35583)
9. [FoxA proteins regulate H19 endoderm enhancer E1 and exhibit developmental changes in enhancer binding in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
10. [Gata4 expression in lateral mesoderm is downstream of BMP4 and is activated directly by Forkhead and GATA transcription factors through a distal enhancer element](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
11. [Plasticity and expanding complexity of the hepatic transcription factor network during liver development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
12. [The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
13. [MOZ regulates the Tbx1 locus, and Moz mutation partially phenocopies DiGeorge syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
14. [The WNT7b promoter is regulated by TTF-1, GATA6, and Foxa2 in lung epithelium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
15. [Siah2-dependent concerted activity of HIF and FoxA2 regulates formation of neuroendocrine phenotype and neuroendocrine prostate tumors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
16. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35583&geneProductId=UniProtKB:P35583)
17. [Conserved transcriptional regulatory domains of the pdx-1 gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
18. [Genome-wide location analysis reveals distinct transcriptional circuitry by paralogous regulators Foxa1 and Foxa2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
19. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35583&geneProductId=UniProtKB:P35583)
20. [Transcriptome analysis for Notch3 target genes identifies Grip2 as a novel regulator of myogenic response in the cerebrovasculature](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
21. [Identification and characterization of a 315-base pair enhancer, located more than 55 kilobases 5' of the apolipoprotein B gene, that confers expression in the intestine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
22. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
23. [Genome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
24. [Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
25. [Immunohistochemical localization of Foxa1 and Foxa2 in mouse embryos and adult tissues](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35583&geneProductId=UniProtKB:P35583)
26. [Thyroid transcription factor-1, hepatocyte nuclear factor-3beta, surfactant protein B, C, and Clara cell secretory protein in developing mouse lung](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35583&geneProductId=UniProtKB:P35583)
27. [The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35583&geneProductId=UniProtKB:P35583)
28. [Foxa1 and Foxa2 Are Required for Formation of the Intervertebral Discs](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35583&geneProductId=UniProtKB:P35583)
29. [Hex homeobox gene controls the transition of the endoderm to a pseudostratified, cell emergent epithelium for liver bud development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35583&geneProductId=UniProtKB:P35583)
30. [Thyroid transcription factor-1, hepatocyte nuclear factor-3beta, surfactant protein B, C, and Clara cell secretory protein in developing mouse lung](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
31. [Hex homeobox gene controls the transition of the endoderm to a pseudostratified, cell emergent epithelium for liver bud development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
32. [Foxa1 and Foxa2 Are Required for Formation of the Intervertebral Discs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
33. [Immunohistochemical localization of Foxa1 and Foxa2 in mouse embryos and adult tissues](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
34. [Lhx1 functions together with Otx2, Foxa2, and Ldb1 to govern anterior mesendoderm, node, and midline development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
35. [Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
36. [HNF3beta and Lim1 interact in the visceral endoderm to regulate primitive streak formation and anterior-posterior polarity in the mouse embryo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
37. [ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
38. [Compensatory roles of Foxa1 and Foxa2 during lung morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
39. [Foxa2 (HNF3beta ) controls multiple genes implicated in metabolism-secretion coupling of glucose-induced insulin release](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
40. [Defects of the body plan of mutant embryos lacking Lim1, Otx2 or Hnf3beta activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
41. [A hepatocyte nuclear factor-3 site in the fibrinogen beta promoter is important for interleukin 6-induced expression, and its activity is influenced by the adjacent -148C/T polymorphism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
42. [goosecoid and HNF-3β genetically interact to regulate neural tube patterning during mouse embryogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35583&geneProductId=UniProtKB:P35583)
43. [Foxa1 and Foxa2 regulate multiple phases of midbrain dopaminergic neuron development in a dosage-dependent manner](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
44. [The foxa2 gene controls the birth and spontaneous degeneration of dopamine neurons in old age](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
45. [Winged-helix, Hedgehog and Bmp genes are differentially expressed in distinct cell layers of the murine yolk sac](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
46. [Foxa2 is required for the differentiation of pancreatic alpha-cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
47. [Transcriptional repression coordinates the temporal switch from motor to serotonergic neurogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
48. [goosecoid and HNF-3β genetically interact to regulate neural tube patterning during mouse embryogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
49. [FKBP8 cell-autonomously controls neural tube patterning through a Gli2- and Kif3a-dependent mechanism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)
50. [The zinc finger-containing transcription factor Gata-4 is expressed in the developing endocrine pancreas and activates glucagon gene expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35583)