# fms related receptor tyrosine kinase 3

> mammalian protein found in Homo sapiens

**Wikidata**: [Q5009781](https://www.wikidata.org/wiki/Q5009781)  
**Source**: https://4ort.xyz/entity/fms-related-receptor-tyrosine-kinase-3


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL2103851)
4. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL574738)
5. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL482968)
6. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1278146)
7. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL3301622)
8. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1944698)
9. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL124660)
10. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P36888)
11. Q20641742
12. [Human FLT3/FLK2 gene: cDNA cloning and expression in hematopoietic cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36888)
13. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36888)
14. [Structural and functional alterations of FLT3 in acute myeloid leukemia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36888)
15. [Src-like adaptor protein 2 (SLAP2) binds to and inhibits FLT3 signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36888)
16. [Association of the protein-tyrosine phosphatase DEP-1 with its substrate FLT3 visualized by in situ proximity ligation assay](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36888)
17. [Constitutive c-jun N-terminal kinase activity in acute myeloid leukemia derives from Flt3 and affects survival and proliferation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36888)
18. [Expanding the substantial interactome of NEMO using protein microarrays](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36888)
19. [SYK is a critical regulator of FLT3 in acute myeloid leukemia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36888)
20. [ABL2 suppresses FLT3-ITD-induced cell proliferation through negative regulation of AKT signaling.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36888)
21. [FLT3 signals via the adapter protein Grb10 and overexpression of Grb10 leads to aberrant cell proliferation in acute myeloid leukemia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36888)
22. [Structural and functional alterations of FLT3 in acute myeloid leukemia](http://www.ebi.ac.uk/QuickGO/annotations?protein=P36888&geneProductId=UniProtKB:P36888)
23. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P36888&geneProductId=UniProtKB:P36888)
24. [The structural basis for autoinhibition of FLT3 by the juxtamembrane domain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36888)
25. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P36888&geneProductId=UniProtKB:P36888)
26. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36888)
27. [Human FLT3/FLK2 gene: cDNA cloning and expression in hematopoietic cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P36888&geneProductId=UniProtKB:P36888)
28. [STK-1, the human homolog of Flk-2/Flt-3, is selectively expressed in CD34+ human bone marrow cells and is involved in the proliferation of early progenitor/stem cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P36888&geneProductId=UniProtKB:P36888)
29. [The role of FLT3 in haematopoietic malignancies](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36888)
30. [STK-1, the human homolog of Flk-2/Flt-3, is selectively expressed in CD34+ human bone marrow cells and is involved in the proliferation of early progenitor/stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36888)
31. Ensembl Release 99
32. Identifiers.org
33. UMLS 2023