# FMS-like tyrosine kinase 3

> mammalian protein found in Mus musculus

**Wikidata**: [Q14912405](https://www.wikidata.org/wiki/Q14912405)  
**Source**: https://4ort.xyz/entity/fms-like-tyrosine-kinase-3


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q00342)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00342)
5. [Substrate specificities and identification of a putative binding site for PI3K in the carboxy tail of the murine Flt3 receptor tyrosine kinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00342)
6. [Identification and characterization of a functional murine FLT3 isoform produced by exon skipping](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00342)
7. [Dual retrovirus integration tagging: identification of new signaling molecules Fiz1 and Hipk2 that are involved in the IL-7 signaling pathway in B lymphoblastic lymphomas](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00342)
8. [Biochemical and genetic characterization of multiple splice variants of the Flt3 ligand](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00342)
9. [Molecular cloning of a ligand for the flt3/flk-2 tyrosine kinase receptor: a proliferative factor for primitive hematopoietic cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00342)
10. [Fiz1, a novel zinc finger protein interacting with the receptor tyrosine kinase Flt3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00342)
11. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00342&geneProductId=UniProtKB:Q00342)
12. [Biochemical characterization and analysis of the transforming potential of the FLT3/FLK2 receptor tyrosine kinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00342)
13. [The E3 ubiquitin ligases RNF126 and Rabring7 regulate endosomal sorting of the Epidermal Growth Factor Receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00342)
14. [The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00342)
15. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00342&geneProductId=UniProtKB:Q00342)
16. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00342)
17. [Flt3/Flk-2 and c-Kit are not essential for the proliferation of B lymphoid progenitor cells in the bone marrow of the adult mouse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00342)
18. [Expression of the flt3 receptor and its ligand on hematopoietic cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00342)
19. [The Src homology 2 protein Shb promotes cell cycle progression in murine hematopoietic stem cells by regulation of focal adhesion kinase activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00342)
20. [Flt3 permits survival during infection by rendering dendritic cells competent to activate NK cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00342)
21. [Key role of flt3 ligand in regulation of the common lymphoid progenitor but not in maintenance of the hematopoietic stem cell pool](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00342&geneProductId=UniProtKB:Q00342)
22. [Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00342)
23. [Mll partial tandem duplication and Flt3 internal tandem duplication in a double knock-in mouse recapitulates features of counterpart human acute myeloid leukemias](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00342)
24. [Repression of Flt3 by Pax5 is crucial for B-cell lineage commitment](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00342)
25. [Cellular and molecular characterization of the role of the flk-2/flt-3 receptor tyrosine kinase in hematopoietic stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00342)
26. [Defective nonhomologous end joining blocks B-cell development in FLT3/ITD mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00342&geneProductId=UniProtKB:Q00342)
27. [The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00342&geneProductId=UniProtKB:Q00342)
28. [Defective nonhomologous end joining blocks B-cell development in FLT3/ITD mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00342)
29. [Impact of gene dosage, loss of wild-type allele, and FLT3 ligand on Flt3-ITD-induced myeloproliferation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00342)
30. [Knock-in of an internal tandem duplication mutation into murine FLT3 confers myeloproliferative disease in a mouse model](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00342)
31. [STK-1, the human homolog of Flk-2/Flt-3, is selectively expressed in CD34+ human bone marrow cells and is involved in the proliferation of early progenitor/stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00342)
32. [Key role of flt3 ligand in regulation of the common lymphoid progenitor but not in maintenance of the hematopoietic stem cell pool](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00342)
33. ensembl Release 106