# FMRP translational regulator 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q905435](https://www.wikidata.org/wiki/Q905435)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/FMR1)  
**Source**: https://4ort.xyz/entity/fmrp-translational-regulator-1


## References

1. UniProt
2. Q20641742
3. [The fragile X mental retardation syndrome protein interacts with novel homologs FXR1 and FXR2](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06787&geneProductId=UniProtKB:Q06787)
4. [Essential role for KH domains in RNA binding: impaired RNA binding by a mutation in the KH domain of FMR1 that causes fragile X syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
5. [The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
6. [Subcellular fractionation and localization studies reveal a direct interaction of the fragile X mental retardation protein (FMRP) with nucleolin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
7. [82-FIP, a novel FMRP (fragile X mental retardation protein) interacting protein, shows a cell cycle-dependent intracellular localization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
8. [Evidence that fragile X mental retardation protein is a negative regulator of translation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
9. [Transport kinetics of FMRP containing the I304N mutation of severe fragile X syndrome in neurites of living rat PC12 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
10. [The C terminus of fragile X mental retardation protein interacts with the multi-domain Ran-binding protein in the microtubule-organising centre](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
11. [The nuclear microspherule protein 58 is a novel RNA-binding protein that interacts with fragile X mental retardation protein in polyribosomal mRNPs from neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
12. [Fragile X mental retardation protein FMRP binds mRNAs in the nucleus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
13. [Fragile X mental retardation protein stimulates ribonucleoprotein assembly of influenza A virus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
14. [Evidence for the association of the human regulatory protein Ki-1/57 with the translational machinery.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
15. [MOV10 and FMRP regulate AGO2 association with microRNA recognition elements](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
16. [The fragile X mental retardation syndrome protein interacts with novel homologs FXR1 and FXR2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
17. [In vitro and in cellulo evidences for association of the survival of motor neuron complex with the fragile X mental retardation protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
18. [A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
19. [The structure of the N-terminal domain of the fragile X mental retardation protein: a platform for protein-protein interaction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
20. [A novel RNA-binding nuclear protein that interacts with the fragile X mental retardation (FMR1) protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
21. [Plakophilins 1 and 3 bind to FXR1 and thereby influence the mRNA stability of desmosomal proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
22. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
23. [FMR1 Protein: Conserved RNP Family Domains and Selective RNA Binding](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06787&geneProductId=UniProtKB:Q06787)
24. [Independent role for presynaptic FMRP revealed by an FMR1 missense mutation associated with intellectual disability and seizures](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06787&geneProductId=UniProtKB:Q06787)
25. [Evidence that fragile X mental retardation protein is a negative regulator of translation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06787&geneProductId=UniProtKB:Q06787)
26. [Fragile X mental retardation protein FMRP binds mRNAs in the nucleus](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06787&geneProductId=UniProtKB:Q06787)
27. [The G-quartet containing FMRP binding site in FMR1 mRNA is a potent exonic splicing enhancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
28. [Dicer-derived microRNAs are utilized by the fragile X mental retardation protein for assembly on target RNAs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
29. [A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06787&geneProductId=UniProtKB:Q06787)
30. [A novel function for fragile X mental retardation protein in translational activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
31. [A chromatin-dependent role of the fragile X mental retardation protein FMRP in the DNA damage response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
32. [The fragile X mental retardation protein binds and regulates a novel class of mRNAs containing U rich target sequences](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
33. [FMRP targets distinct mRNA sequence elements to regulate protein expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
34. [Independent role for presynaptic FMRP revealed by an FMR1 missense mutation associated with intellectual disability and seizures](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
35. [Kissing complex RNAs mediate interaction between the Fragile-X mental retardation protein KH2 domain and brain polyribosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
36. [Essential role for KH domains in RNA binding: impaired RNA binding by a mutation in the KH domain of FMR1 that causes fragile X syndrome](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06787&geneProductId=UniProtKB:Q06787)
37. [Dissecting FMR1, the protein responsible for fragile X syndrome, in its structural and functional domains](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06787&geneProductId=UniProtKB:Q06787)
38. [Plakophilins 1 and 3 bind to FXR1 and thereby influence the mRNA stability of desmosomal proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06787&geneProductId=UniProtKB:Q06787)
39. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06787&geneProductId=UniProtKB:Q06787)
40. [The C terminus of fragile X mental retardation protein interacts with the multi-domain Ran-binding protein in the microtubule-organising centre](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06787&geneProductId=UniProtKB:Q06787)
41. [Insights into RNA biology from an atlas of mammalian mRNA-binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06787&geneProductId=UniProtKB:Q06787)
42. [The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06787&geneProductId=UniProtKB:Q06787)
43. [On the aggregation properties of FMRP--a link with the FXTAS syndrome?](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
44. [Fragile X mental retardation syndrome: structure of the KH1-KH2 domains of fragile X mental retardation protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
45. [Dissecting FMR1, the protein responsible for fragile X syndrome, in its structural and functional domains](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
46. [The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
47. [Insights into RNA biology from an atlas of mammalian mRNA-binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
48. [FMR1 Protein: Conserved RNP Family Domains and Selective RNA Binding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
49. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)
50. [A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06787)