# Flotillin 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21116126](https://www.wikidata.org/wiki/Q21116126)  
**Source**: https://4ort.xyz/entity/flotillin-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O75955)
3. Q20641742
4. [Flotillins bind to the dileucine sorting motif of β-site amyloid precursor protein-cleaving enzyme 1 and influence its endosomal sorting](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955)
6. [The kinesin KIF9 and reggie/flotillin proteins regulate matrix degradation by macrophage podosomes.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955)
7. [Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955)
8. [Analysis of close associations of uropod-associated proteins in human T-cells using the proximity ligation assay](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955)
9. [The intracellular domain of amyloid precursor protein interacts with flotillin-1, a lipid raft protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955)
10. [Role of dynamin and clathrin in the cellular trafficking of flotillins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955)
11. [Arginase-flotillin interaction brings arginase to red blood cell membrane](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955)
12. [Association of ABCA1 with syntaxin 13 and flotillin-1 and enhanced phagocytosis in tangier cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955)
13. [Dynamic reorganization of flotillins in chemokine-stimulated human T-lymphocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955)
14. [Flotillin and epidermal surface antigen define a new family of caveolae-associated integral membrane proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=O75955&geneProductId=UniProtKB:O75955)
15. [A Protein Interaction Network for Ecm29 Links the 26 S Proteasome to Molecular Motors and Endosomal Components](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955)
16. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O75955&geneProductId=UniProtKB:O75955)
17. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=O75955&geneProductId=UniProtKB:O75955)
18. [Flotillin-2 expression in the human gut: from a cell model to human tissue in health and inflammatory bowel diseases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955)
19. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?protein=O75955&geneProductId=UniProtKB:O75955)
20. [Dynamic reorganization of flotillins in chemokine-stimulated human T-lymphocytes](http://www.ebi.ac.uk/QuickGO/annotations?protein=O75955&geneProductId=UniProtKB:O75955)
21. [Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT](http://www.ebi.ac.uk/QuickGO/annotations?protein=O75955&geneProductId=UniProtKB:O75955)
22. [Novel interaction partners of Bardet-Biedl syndrome proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955)
23. [Integral and associated lysosomal membrane proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=O75955&geneProductId=UniProtKB:O75955)
24. [Flotillin microdomains stabilize cadherins at cell-cell junctions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955)
25. [Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955)
26. [Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955)
27. [Flotillin and epidermal surface antigen define a new family of caveolae-associated integral membrane proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955)
28. [Syntenin regulates TGF-β1-induced Smad activation and the epithelial-to-mesenchymal transition by inhibiting caveolin-mediated TGF-β type I receptor internalization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955)
29. [Characterization of the human COP9 signalosome complex using affinity purification and mass spectrometry](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955)
30. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=O75955&geneProductId=UniProtKB:O75955)
31. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=O75955&geneProductId=UniProtKB:O75955)
32. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=O75955&geneProductId=UniProtKB:O75955)
33. [MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=O75955&geneProductId=UniProtKB:O75955)
34. [E-cadherin interactome complexity and robustness resolved by quantitative proteomics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955)
35. [Integral and associated lysosomal membrane proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955)
36. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955)
37. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955)
38. [MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955)
39. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955)
40. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955)
41. [Downregulation of miR-138 sustains NF-κB activation and promotes lipid raft formation in esophageal squamous cell carcinoma.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75955)
42. Ensembl Release 99
43. [Identifiers.org](https://registry.identifiers.org/registry/uniprot)
44. Transporter Classification database