# FKBP prolyl isomerase 1A

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21110396](https://www.wikidata.org/wiki/Q21110396)  
**Source**: https://4ort.xyz/entity/fkbp-prolyl-isomerase-1a


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL219410)
4. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P62942)
5. Q20641742
6. [In situ modulation of the human cardiac ryanodine receptor (hRyR2) by FKBP12.6](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62942&geneProductId=UniProtKB:P62942)
7. [FKBP12 functions as an adaptor of the Smad7-Smurf1 complex on activin type I receptor](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62942&geneProductId=UniProtKB:P62942)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62942&geneProductId=UniProtKB:P62942)
9. [Neointimal expression of rapamycin receptor FK506-binding protein FKBP12: postinjury animal and human in-stent restenosis tissue characteristics](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62942&geneProductId=UniProtKB:P62942)
10. [Receptor accessory folding helper enzymes: the functional role of peptidyl prolyl cis/trans isomerases](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62942&geneProductId=UniProtKB:P62942)
11. [A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62942&geneProductId=UniProtKB:P62942)
12. [The cytosolic-binding protein for the immunosuppressant FK-506 is both a ubiquitous and highly conserved peptidyl-prolyl cis-trans isomerase](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62942&geneProductId=UniProtKB:P62942)
13. [Molecular cloning and overexpression of the human FK506-binding protein FKBP](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62942&geneProductId=UniProtKB:P62942)
14. [Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62942&geneProductId=UniProtKB:P62942)
15. [Further characterization of the type 3 ryanodine receptor (RyR3) purified from rabbit diaphragm](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62942&geneProductId=UniProtKB:P62942)
16. [The FKBP-associated protein FAP48 is an antiproliferative molecule and a player in T cell activation that increases IL2 synthesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62942&geneProductId=UniProtKB:P62942)
17. [FKBP12 regulates the localization and processing of amyloid precursor protein in human cell lines](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62942&geneProductId=UniProtKB:P62942)
18. [A system for quantifying dynamic protein interactions defines a role for Herceptin in modulating ErbB2 interactions](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62942&geneProductId=UniProtKB:P62942)
19. [Protein tag-mediated conjugation of oligonucleotides to recombinant affinity binders for proximity ligation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62942&geneProductId=UniProtKB:P62942)
20. [Refined structure of the FKBP12-rapamycin-FRB ternary complex at 2.2 A resolution](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62942&geneProductId=UniProtKB:P62942)
21. [FKBP binding characteristics of cardiac microsomes from diverse vertebrates](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62942&geneProductId=UniProtKB:P62942)
22. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62942&geneProductId=UniProtKB:P62942)
23. [Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62942&geneProductId=UniProtKB:P62942)
24. [The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62942&geneProductId=UniProtKB:P62942)
25. [Specific interaction of type I receptors of the TGF-beta family with the immunophilin FKBP-12](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62942&geneProductId=UniProtKB:P62942)
26. [Identification and characterization of the murine FK506 binding protein (FKBP) 12.6 gene](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62942&geneProductId=UniProtKB:P62942)
27. [A Novel FK506 Binding Protein Can Mediate the Immunosuppressive Effects of FK506 and Is Associated with the Cardiac Ryanodine Receptor](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62942&geneProductId=UniProtKB:P62942)
28. [FK506 binding protein associated with the calcium release channel (ryanodine receptor)](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62942&geneProductId=UniProtKB:P62942)
29. [Kinetics of FKBP12.6 binding to ryanodine receptors in permeabilized cardiac myocytes and effects on Ca sparks](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62942&geneProductId=UniProtKB:P62942)
30. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62942&geneProductId=UniProtKB:P62942)
31. [FK506 binding protein 12 differentially accelerates fibril formation of wild type alpha-synuclein and its clinical mutants A30P or A53T](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62942&geneProductId=UniProtKB:P62942)
32. [Chromosomal assignment of the human immunophilin FKBP-12 gene](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62942&geneProductId=UniProtKB:P62942)
33. Ensembl Release 99
34. Transporter Classification database