# Fibroblast growth factor receptor substrate 2

> mammalian protein found in Mus musculus

**Wikidata**: [Q21981375](https://www.wikidata.org/wiki/Q21981375)  
**Source**: https://4ort.xyz/entity/fibroblast-growth-factor-receptor-substrate-2-q21981375


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q8C180)
3. Q20641742
4. [A Lipid-Anchored Grb2-Binding Protein That Links FGF-Receptor Activation to the Ras/MAPK Signaling Pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C180)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C180)
6. [Efficient suppression of FGF-2-induced ERK activation by the cooperative interaction among mammalian Sprouty isoforms](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C180)
7. [Interaction Domains of Sos1/Grb2 Are Finely Tuned for Cooperative Control of Embryonic Stem Cell Fate](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C180)
8. [Six post-implantation lethal knockouts of genes for lipophilic MAPK pathway proteins are expressed in preimplantation mouse embryos and trophoblast stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C180)
9. [The Role of Fibroblast Growth Factor Receptor Substrate 2 (FRS2) in the Regulation of Two Activity Levels of the Components of the Extracellular Signal-Regulated Kinase (ERK) Pathway in the Mouse Epididymis1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C180)
10. [Generation of an Frs2α conditional null allele](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C180)
11. [Tyrosine phosphorylation sites on FRS2α responsible for Shp2 recruitment are critical for induction of lens and retina](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C180)
12. [The Docking Protein FRS2α Is an Essential Component of Multiple Fibroblast Growth Factor Responses during Early Mouse Development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C180)
13. [Frs2α enhances fibroblast growth factor-mediated survival and differentiation in lens development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C180)
14. [Role of epithelial cell fibroblast growth factor receptor substrate 2α in prostate development, regeneration and tumorigenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C180)
15. [Essential role of Shp2-binding sites on FRS2α for corticogenesis and for FGF2-dependent proliferation of neural progenitor cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C180)
16. ensembl Release 106