# fibroblast growth factor receptor 3

> mammalian protein found in Homo sapiens

**Wikidata**: [Q5446457](https://www.wikidata.org/wiki/Q5446457)  
**Source**: https://4ort.xyz/entity/fibroblast-growth-factor-receptor-3


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL502835)
4. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1908391)
5. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1852688)
6. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL377300)
7. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL482968)
8. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL3545376)
9. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL274654)
10. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P22607)
11. Q20641742
12. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22607)
13. [Insights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22607)
14. [Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22607)
15. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22607&geneProductId=UniProtKB:P22607)
16. [Fibroblast growth factor (FGF) homologous factors share structural but not functional homology with FGFs](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22607&geneProductId=UniProtKB:P22607)
17. [Receptor specificity of the fibroblast growth factor family](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22607&geneProductId=UniProtKB:P22607)
18. [Transformation and Stat activation by derivatives of FGFR1, FGFR3, and FGFR4](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22607&geneProductId=UniProtKB:P22607)
19. [Identification of tyrosine residues in constitutively activated fibroblast growth factor receptor 3 involved in mitogenesis, Stat activation, and phosphatidylinositol 3-kinase activation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22607&geneProductId=UniProtKB:P22607)
20. [Structure of FGFR3 Transmembrane Domain Dimer: Implications for Signaling and Human Pathologies](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22607)
21. [Structural Mimicry of A-Loop Tyrosine Phosphorylation by a Pathogenic FGF Receptor 3 Mutation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22607)
22. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22607&geneProductId=UniProtKB:P22607)
23. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22607)
24. [Transformation and Stat activation by derivatives of FGFR1, FGFR3, and FGFR4](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22607)
25. [Receptor specificity of the fibroblast growth factor family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22607)
26. [Identification of tyrosine residues in constitutively activated fibroblast growth factor receptor 3 involved in mitogenesis, Stat activation, and phosphatidylinositol 3-kinase activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22607)
27. [The cell surface receptor FGFRL1 forms constitutive dimers that promote cell adhesion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22607)
28. [Cell responses to FGFR3 signalling: growth, differentiation and apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22607)
29. [Generation of Fgfr3 conditional knockout mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22607)
30. [Sustained phosphorylation of mutated FGFR3 is a crucial feature of genetic dwarfism and induces apoptosis in the ATDC5 chondrogenic cell line via PLCgamma-activated STAT1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22607)
31. [Fibroblast growth factor receptor 3 is a negative regulator of bone growth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22607)
32. Ensembl Release 99
33. [Identifiers.org](https://registry.identifiers.org/registry/uniprot)
34. UMLS 2023