# fibroblast growth factor receptor 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q5446453](https://www.wikidata.org/wiki/Q5446453)  
**Source**: https://4ort.xyz/entity/fibroblast-growth-factor-receptor-1-q5446453


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P11362)
4. Q20641742
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11362&geneProductId=UniProtKB:P11362)
7. [Asymmetric receptor contact is required for tyrosine autophosphorylation of fibroblast growth factor receptor in living cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
8. [Novel Recognition Motif on Fibroblast Growth Factor Receptor Mediates Direct Association and Activation of SNT Adapter Proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
9. [Association of CD24 with the kinase c-fgr in a small cell lung cancer cell line and with the kinase lyn in an erythroleukemia cell line](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
10. [Dynamic modulation of FGFR1-5-HT1A heteroreceptor complexes. Agonist treatment enhances participation of FGFR1 and 5-HT1A homodimers and recruitment of β-arrestin2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
11. [Long-Pentraxin 3 Derivative as a Small-Molecule FGF Trap for Cancer Therapy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
12. [Structural basis for FGF receptor dimerization and activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
13. [Fibroblast growth factor receptor 1- 5-hydroxytryptamine 1A heteroreceptor complexes and their enhancement of hippocampal plasticity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
14. [Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
15. [FGF-1 and FGF-2 modulate the E-cadherin/catenin system in pancreatic adenocarcinoma cell lines](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
16. [Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
17. [Myeloproliferative disorder FOP-FGFR1 fusion kinase recruits phosphoinositide-3 kinase and phospholipase Cgamma at the centrosome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
18. [The selectivity of receptor tyrosine kinase signaling is controlled by a secondary SH2 domain binding site](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
19. [Structural and Functional Integration of the PLCγ Interaction Domains Critical for Regulatory Mechanisms and Signaling Deregulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
20. [The F-BAR protein NOSTRIN participates in FGF signal transduction and vascular development.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
21. [Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
22. [Grb14 inhibits FGF receptor signaling through the regulation of PLCγ recruitment and activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
23. [Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
24. [Novel mechanisms of fibroblast growth factor receptor 1 regulation by extracellular matrix protein anosmin-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
25. [Control of fibroblast growth factor receptor kinase signal transduction by heterodimerization of combinatorial splice variants](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
26. [Nedd4-1 binds and ubiquitylates activated FGFR1 to control its endocytosis and function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
27. [Molecular mechanism of SSR128129E, an extracellularly acting, small-molecule, allosteric inhibitor of FGF receptor signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
28. [Direct binding of integrin alphavbeta3 to FGF1 plays a role in FGF1 signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
29. [A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
30. [Fibroblast growth factor receptor-1-mediated endothelial cell proliferation is dependent on the Src homology (SH) 2/SH3 domain-containing adaptor protein Crk](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
31. [Receptor specificity of the fibroblast growth factor family](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11362&geneProductId=UniProtKB:P11362)
32. [Ubiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11362&geneProductId=UniProtKB:P11362)
33. [Diverse forms of a receptor for acidic and basic fibroblast growth factors](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11362&geneProductId=UniProtKB:P11362)
34. [A novel type I fibroblast growth factor receptor activates mitogenic signaling in the absence of detectable tyrosine phosphorylation of FRS2](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11362&geneProductId=UniProtKB:P11362)
35. [Asymmetric receptor contact is required for tyrosine autophosphorylation of fibroblast growth factor receptor in living cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11362&geneProductId=UniProtKB:P11362)
36. [Ubiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
37. [Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11362&geneProductId=UniProtKB:P11362)
38. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11362&geneProductId=UniProtKB:P11362)
39. [Diverse forms of a receptor for acidic and basic fibroblast growth factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
40. [A novel type I fibroblast growth factor receptor activates mitogenic signaling in the absence of detectable tyrosine phosphorylation of FRS2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
41. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
42. [Receptor specificity of the fibroblast growth factor family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
43. [Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
44. [The human fibroblast growth factor receptor genes: a common structural arrangement underlies the mechanisms for generating receptor forms that differ in their third immunoglobulin domain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
45. [Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11362&geneProductId=UniProtKB:P11362)
46. [Transformation and Stat activation by derivatives of FGFR1, FGFR3, and FGFR4](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11362&geneProductId=UniProtKB:P11362)
47. [Complete sequence of a human receptor for acidic and basic fibroblast growth factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
48. [Fibroblast Growth Factor Receptors from Liver Vary in Three Structural Domains](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
49. [Transformation and Stat activation by derivatives of FGFR1, FGFR3, and FGFR4](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)
50. [Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11362)