# Fibroblast growth factor 8

> mammalian protein found in Mus musculus

**Wikidata**: [Q21985352](https://www.wikidata.org/wiki/Q21985352)  
**Source**: https://4ort.xyz/entity/fibroblast-growth-factor-8-q21985352


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P37237)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P37237&geneProductId=UniProtKB:P37237)
6. [Analysis of the regulation of lin-41 during chick and mouse limb development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
7. [FGF8 dose-dependent regulation of embryonic submandibular salivary gland morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
8. [Sonic hedgehog signaling plays an essential role during embryonic salivary gland epithelial branching morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
9. [Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
10. [The role of Nurr1 in the development of dopaminergic neurons and Parkinson's disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
11. [Sprouty2, a mouse deafness gene, regulates cell fate decisions in the auditory sensory epithelium by antagonizing FGF signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
12. [Loss of Bmp7 and Fgf8 signaling in Hoxa13-mutant mice causes hypospadia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
13. [The roles of Fgf4 and Fgf8 in limb bud initiation and outgrowth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
14. [Differences in left-right axis pathways in mouse and chick: functions of FGF8 and SHH](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
15. [Integrated FGF and BMP signaling controls the progression of progenitor cell differentiation and the emergence of pattern in the embryonic anterior pituitary](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
16. [FGF8 initiates inner ear induction in chick and mouse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
17. [Inactivation of FGF8 in early mesoderm reveals an essential role in kidney development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
18. [Murine Jagged1/Notch signaling in the second heart field orchestrates Fgf8 expression and tissue-tissue interactions during outflow tract development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
19. [A Tbx1-Six1/Eya1-Fgf8 genetic pathway controls mammalian cardiovascular and craniofacial morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
20. [Dose-dependent functions of Fgf8 in regulating telencephalic patterning centers](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
21. [Fgf8 expression in the Tbx1 domain causes skeletal abnormalities and modifies the aortic arch but not the outflow tract phenotype of Tbx1 mutants](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
22. [ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
23. [Early thyroid development requires a Tbx1-Fgf8 pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
24. [Fgf8 is required for anterior heart field development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
25. [Antagonistic Interactions between FGF and BMP Signaling Pathways: A Mechanism for Positioning the Sites of Tooth Formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
26. [Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
27. [Fgf8 expression defines a morphogenetic center required for olfactory neurogenesis and nasal cavity development in the mouse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
28. [Required, tissue-specific roles for Fgf8 in outflow tract formation and remodeling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
29. [Partial rescue of the Tbx1 mutant heart phenotype by Fgf8: genetic evidence of impaired tissue response to Fgf8](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
30. [Ablation of specific expression domains reveals discrete functions of ectoderm- and endoderm-derived FGF8 during cardiovascular and pharyngeal development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
31. [Genomic structure, mapping, activity and expression of fibroblast growth factor 17](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
32. [Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
33. [Dissection of Tbx1 and Fgf interactions in mouse models of 22q11DS suggests functional redundancy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
34. [Conserved regulation of mesenchymal gene expression by Fgf-8 in face and limb development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
35. [Differential requirements for FGF3, FGF8 and FGF10 during inner ear development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
36. [Shp2-dependent ERK signaling is essential for induction of Bergmann glia and foliation of the cerebellum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
37. [Loss of Gbx2 results in neural crest cell patterning and pharyngeal arch artery defects in the mouse embryo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
38. [Differentiation of the lateral compartment of the cochlea requires a temporally restricted FGF20 signal](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
39. [Structural and functional basis of a role for CRKL in a fibroblast growth factor 8-induced feed-forward loop](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
40. [Crkl deficiency disrupts Fgf8 signaling in a mouse model of 22q11 deletion syndromes.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37237)
41. ensembl Release 106