# Fibroblast growth factor 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q14866180](https://www.wikidata.org/wiki/Q14866180)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Fibroblast_growth_factor_2)  
**Source**: https://4ort.xyz/entity/fibroblast-growth-factor-2


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P09038)
3. Q20641742
4. [The zinc-finger transcription factor, early growth response 3, mediates VEGF-induced angiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
6. [Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
7. [A murine fibroblast growth factor (FGF) receptor expressed in CHO cells is activated by basic FGF and Kaposi FGF](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
8. [Translokin is an intracellular mediator of FGF-2 trafficking](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
9. [FIF [fibroblast growth factor-2 (FGF-2)-interacting-factor], a nuclear putatively antiapoptotic factor, interacts specifically with FGF-2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
10. [Long-Pentraxin 3 Derivative as a Small-Molecule FGF Trap for Cancer Therapy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
11. [Structural basis for FGF receptor dimerization and activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
12. [Structural basis for fibroblast growth factor receptor 2 activation in Apert syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
13. [Klotho converts canonical FGF receptor into a specific receptor for FGF23](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
14. [Identification of the fibroblast growth factor (FGF)-interacting domain in a secreted FGF-binding protein by phage display](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
15. [Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
16. [Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
17. [Active caspase-1 is a regulator of unconventional protein secretion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
18. [Molecular mechanism of SSR128129E, an extracellularly acting, small-molecule, allosteric inhibitor of FGF receptor signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
19. [Long pentraxin 3/tumor necrosis factor-stimulated gene-6 interaction: a biological rheostat for fibroblast growth factor 2-mediated angiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
20. [The angiogenic inhibitor long pentraxin PTX3 forms an asymmetric octamer with two binding sites for FGF2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
21. [Fibroblast Growth Factor-2 Interacts with Free Ribosomal Protein S19](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
22. [Regulation of secreted Frizzled-related protein-1 by heparin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
23. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P09038&geneProductId=UniProtKB:P09038)
24. [Dynamic modulation of FGFR1-5-HT1A heteroreceptor complexes. Agonist treatment enhances participation of FGFR1 and 5-HT1A homodimers and recruitment of β-arrestin2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
25. [The integrin-binding defective FGF2 mutants potently suppress FGF2 signalling and angiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
26. [Cloning and expression of cDNA encoding human basic fibroblast growth factor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
27. [A phosphoinositide 3-kinase/phospholipase Cgamma1 pathway regulates fibroblast growth factor-induced capillary tube formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
28. [bFGF induces changes in hyaluronan synthase and hyaluronidase isoform expression and modulates the migration capacity of fibrosarcoma cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
29. [Fibroblast growth factor 16 and 18 are expressed in human cardiovascular tissues and induce on endothelial cells migration but not proliferation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
30. [Differential involvement of TGF-beta1 in mediating the motogenic effects of TSP-1 on endothelial cells, fibroblasts and oral tumour cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
31. [Evidence that bone morphogenetic protein 4 has multiple biological functions during kidney and urinary tract development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
32. [Neuronal defects and delayed wound healing in mice lacking fibroblast growth factor 2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
33. [HDAC5 is a repressor of angiogenesis and determines the angiogenic gene expression pattern of endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
34. [The integrin-binding defective FGF2 mutants potently suppress FGF2 signalling and angiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P09038&geneProductId=UniProtKB:P09038)
35. [A phosphoinositide 3-kinase/phospholipase Cgamma1 pathway regulates fibroblast growth factor-induced capillary tube formation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P09038&geneProductId=UniProtKB:P09038)
36. [Involvement of Ras and Ral in chemotactic migration of skeletal myoblasts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
37. [Receptor specificity of the fibroblast growth factor family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
38. [The novel SPARC family member SMOC-2 potentiates angiogenic growth factor activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
39. [Fibroblast growth factors 2, 4, and 8 exert both negative and positive effects on limb, frontonasal, and mandibular chondrogenesis via MEK-ERK activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
40. [The role of syndecan-4 and attached glycosaminoglycan chains on myogenic satellite cell growth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
41. [Neuregulins promote survival and growth of cardiac myocytes. Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
42. [Crucial role of vHNF1 in vertebrate hepatic specification](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
43. [Signaling and transcriptional regulation in early mammalian eye development: a link between FGF and MITF](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
44. [Nerve Growth Factor Regulation of m4 Muscarinic Receptor mRNA Stability but Not Gene Transcription Requires Mitogen-activated Protein Kinase Activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
45. [A dominant-negative FGF1 mutant (the R50E mutant) suppresses tumorigenesis and angiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
46. [Functional consequences of 17q21.31/WNT3-WNT9B amplification in hPSCs with respect to neural differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
47. [An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertension](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09038)
48. Ensembl Release 99
49. Transporter Classification database