# Fibroblast growth factor 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q5425464](https://www.wikidata.org/wiki/Q5425464)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Fibroblast_growth_factor_1)  
**Source**: https://4ort.xyz/entity/fibroblast-growth-factor-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P05230)
3. Q20641742
4. [Copper induces the assembly of a multiprotein aggregate implicated in the release of fibroblast growth factor 1 in response to stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05230)
5. [Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05230)
6. [Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05230)
7. [Structural interactions of fibroblast growth factor receptor with its ligands](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05230)
8. [Insights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05230)
9. [Direct binding of integrin alphavbeta3 to FGF1 plays a role in FGF1 signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05230)
10. [Alternative splicing generates two forms of mRNA coding for human heparin-binding growth factor 1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05230)
11. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05230)
12. [Gentisic acid, a compound associated with plant defense and a metabolite of aspirin, heads a new class of in vivo fibroblast growth factor inhibitors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05230)
13. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P05230&geneProductId=UniProtKB:P05230)
14. [Fibroblast growth factor (FGF) homologous factors share structural but not functional homology with FGFs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05230)
15. [S100A13 mediates the copper-dependent stress-induced release of IL-1α from both human U937 and murine NIH 3T3 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05230)
16. [The release of fibroblast growth factor-1 from melanoma cells requires copper ions and is mediated by phosphatidylinositol 3-kinase/Akt intracellular signaling pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05230)
17. [Fibroblast growth factor 16 and 18 are expressed in human cardiovascular tissues and induce on endothelial cells migration but not proliferation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05230)
18. [FGF-1 induces expression of LXRalpha and production of 25-hydroxycholesterol to upregulate the apoE gene in rat astrocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05230)
19. [Multiple fibroblast growth factors support growth of the ureteric bud but have different effects on branching morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05230)
20. [Signaling and transcriptional regulation in early mammalian eye development: a link between FGF and MITF](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05230)
21. [Amino acid sequence of human acidic fibroblast growth factor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05230)
22. [A dominant-negative FGF1 mutant (the R50E mutant) suppresses tumorigenesis and angiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05230)
23. [betaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05230)
24. [Receptor specificity of the fibroblast growth factor family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05230)
25. Ensembl Release 99
26. UMLS 2023