# Fas cell surface death receptor

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28560116](https://www.wikidata.org/wiki/Q28560116)  
**Source**: https://4ort.xyz/entity/fas-cell-surface-death-receptor-q28560116


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q63199)
3. Q20641742
4. [FasL, Fas, and death-inducing signaling complex (DISC) proteins are recruited to membrane rafts after spinal cord injury](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
5. [A variant mRNA species encoding a truncated form of Fas antigen in the rat liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
7. [Nuclear factor-kappaB mediates Kupffer cell apoptosis through transcriptional activation of Fas/FasL](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
8. [Blocking Daxx trafficking attenuates neuronal cell death following ischemia/reperfusion in rat hippocampus CA1 region](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
9. [Expression of FasL and its interaction with Fas are mediated by c-Jun N-terminal kinase (JNK) pathway in 6-OHDA-induced rat model of Parkinson disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
10. [Fas antigen/CD-95 upregulation and activation during castration-induced regression of the rat ventral prostate gland](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
11. [Rat liver myofibroblasts and hepatic stellate cells differ in CD95-mediated apoptosis and response to TNF-alpha](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
12. [Shedding of Fas ectodomain that affects apoptosis of hepatocytes occurring in regenerative liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
13. [The extracellular matrix, p53 and estrogen compete to regulate cell-surface Fas/Apo-1 suicide receptor expression in proliferating embryonic cerebral cortical precursors, and reciprocally, Fas-ligand modifies estrogen control of cell-cycle proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
14. [Amplification of CD95 activation by caspase 8-induced endosomal acidification in rat hepatocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
15. [Apoptosis of tubular epithelial cells in glycogen nephrosis during diabetes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
16. [Intravesicular Fas localization in epithelial cells of castrated rat prostate glands](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
17. [C5b-9 terminal complex protects oligodendrocytes from apoptotic cell death by inhibiting caspase-8 processing and up-regulating FLIP](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
18. [The cardiac Fas (APO-1/CD95) Receptor/Fas ligand system : relation to diastolic wall stress in volume-overload hypertrophy in vivo and activation of the transcription factor AP-1 in cardiac myocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
19. [Fas/Apo [apoptosis]-1 and associated proteins in the differentiating cerebral cortex: induction of caspase-dependent cell death and activation of NF-kappaB](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
20. [Fas/APO-1/CD95 system as a mediator of granulosa cell apoptosis in ovarian follicle atresia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
21. [IL-6 protects enterocytes from hypoxia-induced apoptosis by induction of bcl-2 mRNA and reduction of fas mRNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
22. [Up-regulation of CD95 (Apo-1/Fas) is associated with spermatocyte apoptosis during the first round of spermatogenesis in the rat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
23. [Aging correlates with decreased beta-cell proliferative capacity and enhanced sensitivity to apoptosis: a potential role for Fas and pancreatic duodenal homeobox-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
24. [Effect of Huwentoxin-I on the Fas and TNF apoptosis pathway in the hippocampus of rat with global cerebral ischemia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
25. [p,p'‐DDE induces apoptosis and mRNA expression of apoptosis‐associated genes in testes of pubertal rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
26. [Study on the effect of iodine excess on cell apoptosis in rat thyroid cells (FRTL)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
27. [Insulin-like growth factor-1 treatment prevents anti-Fas antibody-induced apoptosis in endplate chondrocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
28. [Fas Ligand Gene (Faslg) Plays an Important Role in Nerve Degeneration and Regeneration After Rat Sciatic Nerve Injury](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
29. [Involvement of mitochondrial- and Fas-mediated dual mechanism in CoCl2-induced apoptosis of rat PC12 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
30. [c-Jun N-terminal kinases mediate Fas-induced neurite regeneration in PC12 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
31. [Increased placental apoptosis in maternal food restricted gestations: role of the Fas pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
32. [Protein kinase C-zeta (PKC-zeta) regulates Kupffer cell apoptosis during experimental sepsis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
33. [The effects of interleukin-10 on the expression of Fas and FasL in rat hepatic stellate cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
34. [Fas Ag-FasL coupling leads to ERK1/2-mediated proliferation of gastric mucosal cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
35. [Estrous cycle dependent changes in expression and distribution of Fas, Fas ligand, Bcl-2, Bax, and pro- and active caspase-3 in the rat ovary](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
36. [Expression of Fas and Fas ligand mRNA in rat and human preimplantation embryos](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
37. [Fas inhibition attenuates lipopolysaccharide-induced apoptosis and cytokine release of rat type II alveolar epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
38. [Double role of Fas ligand in the apoptosis of intervertebral disc cells in vitro](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
39. [Thyrotropin releasing hormone (TRH) affects gene expression in pancreatic beta-cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
40. [The Fas/Fas Ligand Death Receptor Pathway Contributes to Phenylalanine-Induced Apoptosis in Cortical Neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
41. [Estrogens up-regulate the Fas/FasL apoptotic pathway in lactotropes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
42. [Rapid induction of Fas antigen mRNA expression in vivo by cycloheximide](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
43. [Fas and Fas ligand messenger ribonucleic acid and protein expression in the rat corpus luteum during apoptosis-mediated luteolysis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
44. [H(2)O(2) induces upregulation of Fas and Fas ligand expression in NGF-differentiated PC12 cells: modulation by cAMP](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
45. [Effects of interleukin-10 on activation and apoptosis of hepatic stellate cells in fibrotic rat liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
46. [Tumor necrosis factor alpha and interleukin 1beta up-regulate gastric mucosal Fas antigen expression in Helicobacter pylori infection](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
47. [The natural compound n-butylidenephthalide derived from Angelica sinensis inhibits malignant brain tumor growth in vitro and in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
48. [Hypoxia predisposes neonatal rat ventricular myocytes to apoptosis induced by activation of the Fas (CD95/Apo-1) receptor: Fas activation and apoptosis in hypoxic myocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
49. [Pressure and endothelial coculture upregulate myocytic Fas-FasL pathway and induce apoptosis by way of direct and paracrine mechanisms](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)
50. [Metabolic loading of guanosine induces chondrocyte apoptosis via the Fas pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63199)