# F-box protein 5

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21100641](https://www.wikidata.org/wiki/Q21100641)  
**Source**: https://4ort.xyz/entity/f-box-protein-5-q21100641


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9UKT4)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKT4)
5. [Emi1 preferentially inhibits ubiquitin chain elongation by the anaphase-promoting complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKT4)
6. [Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKT4)
7. [E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APCCdh1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKT4)
8. [Prophase Destruction of Emi1 by the SCFβTrCP/Slimb Ubiquitin Ligase Activates the Anaphase Promoting Complex to Allow Progression beyond Prometaphase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKT4)
9. [The Cdc14B-Cdh1-Plk1 Axis Controls the G2 DNA-Damage-Response Checkpoint](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKT4)
10. [The Evi5 Oncogene Regulates Cyclin Accumulation by Stabilizing the Anaphase-Promoting Complex Inhibitor Emi1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKT4)
11. [A Bacterial Effector Targets Mad2L2, an APC Inhibitor, to Modulate Host Cell Cycling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKT4)
12. [Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKT4)
13. [Atomic structure of the APC/C and its mechanism of protein ubiquitination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKT4)
14. [Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKT4)
15. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UKT4&geneProductId=UniProtKB:Q9UKT4)
16. [E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APCCdh1](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UKT4&geneProductId=UniProtKB:Q9UKT4)
17. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKT4)
18. [Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UKT4&geneProductId=UniProtKB:Q9UKT4)
19. [Emi1 is needed to couple DNA replication with mitosis but does not regulate activation of the mitotic APC/C](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKT4)
20. [The APC/C inhibitor, Emi1, is essential for prevention of rereplication](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKT4)
21. [Loss of Emi1-Dependent Anaphase-Promoting Complex/Cyclosome Inhibition Deregulates E2F Target Expression and Elicits DNA Damage-Induced Senescence](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKT4)
22. [Two Transcripts of FBXO5 Promote Migration and Osteogenic Differentiation of Human Periodontal Ligament Mesenchymal Stem Cells.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKT4)
23. [EMI1 switches from being a substrate to an inhibitor of APC/CCDH1 to start the cell cycle.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKT4)
24. [Electron microscopy structure of human APC/CCDH1–EMI1 reveals multimodal mechanism of E3 ligase shutdown](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKT4)
25. Ensembl Release 99