# F-box and WD-40 domain protein 7

> mammalian protein found in Mus musculus

**Wikidata**: [Q21495706](https://www.wikidata.org/wiki/Q21495706)  
**Source**: https://4ort.xyz/entity/f-box-and-wd-40-domain-protein-7


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q8VBV4)
3. Q20641742
4. [Functional interaction between SEL-10, an F-box protein, and the nuclear form of activated Notch1 receptor](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8VBV4&geneProductId=UniProtKB:Q8VBV4)
5. [The Fbw7 Tumor Suppressor Regulates Nuclear Factor E2-related Factor 1 Transcription Factor Turnover through Proteasome-mediated Proteolysis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VBV4)
6. [Parkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VBV4)
7. [Nucleophosmin and its AML-associated mutant regulate c-Myc turnover through Fbw7 gamma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VBV4)
8. [Functional interaction between SEL-10, an F-box protein, and the nuclear form of activated Notch1 receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VBV4)
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8VBV4&geneProductId=UniProtKB:Q8VBV4)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VBV4)
11. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VBV4)
12. [Characterization of a mouse gene (Fbxw6) that encodes a homologue of Caenorhabditis elegans SEL-10](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VBV4)
13. [Presenilin modulates EGFR signaling and cell transformation by regulating the ubiquitin ligase Fbw7](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VBV4)
14. [Nucleophosmin and its AML-associated mutant regulate c-Myc turnover through Fbw7 gamma](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8VBV4&geneProductId=UniProtKB:Q8VBV4)
15. [Characterization of a mouse gene (Fbxw6) that encodes a homologue of Caenorhabditis elegans SEL-10](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8VBV4&geneProductId=UniProtKB:Q8VBV4)
16. [Presenilin modulates EGFR signaling and cell transformation by regulating the ubiquitin ligase Fbw7](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8VBV4&geneProductId=UniProtKB:Q8VBV4)
17. [FBXW7 mutations typically found in human cancers are distinct from null alleles and disrupt lung development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VBV4)
18. [FBW7 regulates endothelial functions by targeting KLF2 for ubiquitination and degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VBV4)
19. [SEL-10 interacts with presenilin 1, facilitates its ubiquitination, and alters A-beta peptide production](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8VBV4&geneProductId=UniProtKB:Q8VBV4)
20. [The Fbw7 Tumor Suppressor Regulates Nuclear Factor E2-related Factor 1 Transcription Factor Turnover through Proteasome-mediated Proteolysis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8VBV4&geneProductId=UniProtKB:Q8VBV4)
21. [Parkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8VBV4&geneProductId=UniProtKB:Q8VBV4)
22. [NOTCH2 Hajdu-Cheney Mutations Escape SCFFBW7-Dependent Proteolysis to Promote Osteoporosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8VBV4&geneProductId=UniProtKB:Q8VBV4)
23. [SEL-10 interacts with presenilin 1, facilitates its ubiquitination, and alters A-beta peptide production](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VBV4)
24. [NOTCH2 Hajdu-Cheney Mutations Escape SCFFBW7-Dependent Proteolysis to Promote Osteoporosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VBV4)
25. [Circadian Amplitude Regulation via FBXW7-Targeted REV-ERBα Degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VBV4)
26. ensembl Release 106