Eyes absent homolog 1 CELE_C49A1.4
type: Thing
description: protein found in Caenorhabditis elegans
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P279
  value: protein
additional property: PropertyValue
  property ID: P352
  value: O17670
additional property: PropertyValue
  property ID: P361
  value: EYA domain superfamily
additional property: PropertyValue
  property ID: P361
  value: Eyes absent family
additional property: PropertyValue
  property ID: P361
  value: EYA domain, protein family
additional property: PropertyValue
  property ID: P527
  value: EYA domain
additional property: PropertyValue
  property ID: P637
  value: NP_001021055
additional property: PropertyValue
  property ID: P637
  value: NP_001021056
additional property: PropertyValue
  property ID: P680
  value: transcription coactivator activity
additional property: PropertyValue
  property ID: P680
  value: phosphoprotein phosphatase activity
additional property: PropertyValue
  property ID: P680
  value: protein tyrosine phosphatase activity
additional property: PropertyValue
  property ID: P681
  value: nucleus
additional property: PropertyValue
  property ID: P681
  value: nucleus
additional property: PropertyValue
  property ID: P682
  value: nematode larval development
additional property: PropertyValue
  property ID: P682
  value: transcription, DNA-templated
additional property: PropertyValue
  property ID: P682
  value: regulation of transcription, DNA-templated
additional property: PropertyValue
  property ID: P702
  value: eya-1
additional property: PropertyValue
  property ID: P703
  value: Caenorhabditis elegans
additional property: PropertyValue
  property ID: P705
  value: C49A1.4a
additional property: PropertyValue
  property ID: P705
  value: C49A1.4b
confidence:
  popularity graph score:
    score: 0.002
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 16
      unique citations norm: 0.006
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 16
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P279:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: O17670
    source count: 1
    confidence: 0.2
  P361:
    value: Q54460734
    source count: 1
    confidence: 0.2
    value label: EYA domain superfamily
  P361:
    value: Q24788231
    source count: 1
    confidence: 0.2
    value label: Eyes absent family
  P361:
    value: Q83146900
    source count: 1
    confidence: 0.2
    value label: EYA domain, protein family
  P527:
    value: Q24779383
    source count: 1
    confidence: 0.2
    value label: EYA domain
  P637:
    value: NP_001021055
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001021056
    source count: 1
    confidence: 0.2
  P680:
    value: Q14860440
    source count: 1
    confidence: 0.2
    value label: transcription coactivator activity
  P680:
    value: Q14878340
    source count: 1
    confidence: 0.2
    value label: phosphoprotein phosphatase activity
  P680:
    value: Q14878341
    source count: 4
    confidence: 0.8
    value label: protein tyrosine phosphatase activity
  P680:
    value: Q167149
    source count: 4
    confidence: 0.8
    value label: protein binding
  P680:
    value: Q14353168
    source count: 1
    confidence: 0.2
    value label: hydrolase activity
  P681:
    value: Q40260
    source count: 2
    confidence: 0.4
    value label: nucleus
  P681:
    value: Q40260
    source count: 3
    confidence: 0.6
    value label: nucleus
  P682:
    value: Q22298503
    source count: 2
    confidence: 0.4
    value label: nematode larval development
  P682:
    value: Q14763010
    source count: 1
    confidence: 0.2
    value label: transcription, DNA-templated
  P682:
    value: Q14633883
    source count: 2
    confidence: 0.4
    value label: regulation of transcription, DNA-templated
  P682:
    value: Q14645705
    source count: 2
    confidence: 0.4
    value label: multicellular organism development
  P682:
    value: Q21108740
    source count: 1
    confidence: 0.2
    value label: mesodermal cell fate specification
  P702:
    value: Q29679777
    source count: 1
    confidence: 0.2
    value label: eya-1
  P703:
    value: Q91703
    source count: 1
    confidence: 0.2
    value label: Caenorhabditis elegans
  P705:
    value: C49A1.4a
    source count: 1
    confidence: 0.2
  P705:
    value: C49A1.4b
    source count: 1
    confidence: 0.2

source: The C. elegans eyes absent ortholog EYA-1 is required for tissue differentiation and plays partially redundant roles with PAX-6.
stated in qid: Q46696437
retrieved: 2018-01-01

source: GOA
stated in qid: Q28018111
retrieved: 2018-01-01

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2018-01-01

source: Six and Eya promote apoptosis through direct transcriptional activation of the proapoptotic BH3-only gene egl-1 in Caenorhabditis elegans
stated in qid: Q34100473
retrieved: 2018-01-01

source: Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network
stated in qid: Q34676654
retrieved: 2018-01-01

source: A map of the interactome network of the metazoan C. elegans
stated in qid: Q29547482
retrieved: 2018-01-01

source: Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network
stated in qid: Q37224364
retrieved: 2018-01-01

source: GOA
stated in qid: Q28018111
retrieved: 2018-06-05

source: The C. elegans eyes absent ortholog EYA-1 is required for tissue differentiation and plays partially redundant roles with PAX-6.
stated in qid: Q46696437
retrieved: 2018-06-05

source: Six and Eya promote apoptosis through direct transcriptional activation of the proapoptotic BH3-only gene egl-1 in Caenorhabditis elegans
stated in qid: Q34100473
retrieved: 2018-06-05

source: A conserved Six-Eya cassette acts downstream of Wnt signaling to direct non-myogenic versus myogenic fates in the C. elegans postembryonic mesoderm
stated in qid: Q37245143
retrieved: 2018-01-01

source: Caenorhabditis elegans eyes absent ortholog EYA-1 Is required for stress resistance
stated in qid: Q50319510
retrieved: 2018-01-01

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2019-04-10

source: Q20641742
stated in qid: Q20641742
retrieved: 2019-03-18

source: ensembl Release 96
stated in qid: Q63170780

wikidata id: Q50846261
domain: protein
level: standard
html url: https://4ort.xyz/entity/eyes-absent-homolog-1-cele-c49a1-4
markdown url: https://4ort.xyz/entity/eyes-absent-homolog-1-cele-c49a1-4.md
facts url summary: https://4ort.xyz/entity/eyes-absent-homolog-1-cele-c49a1-4/facts.json
facts url standard: https://4ort.xyz/entity/eyes-absent-homolog-1-cele-c49a1-4/facts.json
facts url full: https://4ort.xyz/entity/eyes-absent-homolog-1-cele-c49a1-4/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-01T20:31:42.932597Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T14:27:54.330319+00:00Z