EYA transcriptional coactivator and phosphatase 1
type: Thing
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P352
  value: Norbert Conrads
additional property: PropertyValue
  property ID: P361
  value: Eyes absent homologue 1
additional property: PropertyValue
  property ID: P361
  value: EYA domain superfamily
additional property: PropertyValue
  property ID: P361
  value: EYA domain, protein family
additional property: PropertyValue
  property ID: P527
  value: EYA domain
additional property: PropertyValue
  property ID: P637
  value: NP_000494
additional property: PropertyValue
  property ID: P637
  value: NP_001275503
additional property: PropertyValue
  property ID: P637
  value: NP_001275504
additional property: PropertyValue
  property ID: P680
  value: phosphoprotein phosphatase activity
additional property: PropertyValue
  property ID: P680
  value: metal ion binding
additional property: PropertyValue
  property ID: P680
  value: protein binding
additional property: PropertyValue
  property ID: P681
  value: cytoplasm
additional property: PropertyValue
  property ID: P681
  value: protein-DNA complex
additional property: PropertyValue
  property ID: P681
  value: nucleus
additional property: PropertyValue
  property ID: P682
  value: pattern specification process
additional property: PropertyValue
  property ID: P682
  value: response to ionizing radiation
additional property: PropertyValue
  property ID: P682
  value: regulation of neuron differentiation
additional property: PropertyValue
  property ID: P702
  value: EYA1
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P705
  value: ENSP00000342626
additional property: PropertyValue
  property ID: P705
  value: ENSP00000373392
additional property: PropertyValue
  property ID: P705
  value: ENSP00000373394
confidence:
  popularity graph score:
    score: 0.002
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 13
      unique citations norm: 0.005
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 13
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: Q99502
    source count: 1
    confidence: 0.2
    value label: Norbert Conrads
  P361:
    value: Q24770120
    source count: 1
    confidence: 0.2
    value label: Eyes absent homologue 1
  P361:
    value: Q54460734
    source count: 1
    confidence: 0.2
    value label: EYA domain superfamily
  P361:
    value: Q83146900
    source count: 1
    confidence: 0.2
    value label: EYA domain, protein family
  P527:
    value: Q24779383
    source count: 1
    confidence: 0.2
    value label: EYA domain
  P637:
    value: NP_000494
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001275503
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001275504
    source count: 1
    confidence: 0.2
  P637:
    value: NP_742055
    source count: 1
    confidence: 0.2
  P637:
    value: NP_742056
    source count: 1
    confidence: 0.2
  P680:
    value: Q14878340
    source count: 1
    confidence: 0.2
    value label: phosphoprotein phosphatase activity
  P680:
    value: Q13667380
    source count: 1
    confidence: 0.2
    value label: metal ion binding
  P680:
    value: Q167149
    source count: 1
    confidence: 0.2
    value label: protein binding
  P680:
    value: Q14330639
    source count: 1
    confidence: 0.2
    value label: RNA binding
  P680:
    value: Q14878341
    source count: 4
    confidence: 0.8
    value label: protein tyrosine phosphatase activity
  P681:
    value: Q79899
    source count: 3
    confidence: 0.6
    value label: cytoplasm
  P681:
    value: Q14888035
    source count: 1
    confidence: 0.2
    value label: protein-DNA complex
  P681:
    value: Q40260
    source count: 4
    confidence: 0.8
    value label: nucleus
  P681:
    value: Q14817956
    source count: 2
    confidence: 0.4
    value label: nucleoplasm
  P681:
    value: Q14817965
    source count: 1
    confidence: 0.2
    value label: nuclear body
  P682:
    value: Q14820048
    source count: 1
    confidence: 0.2
    value label: pattern specification process
  P682:
    value: Q14860451
    source count: 1
    confidence: 0.2
    value label: response to ionizing radiation
  P682:
    value: Q14873933
    source count: 1
    confidence: 0.2
    value label: regulation of neuron differentiation

value: Q14886895
source count: 1
confidence: 0.2
value label: embryonic skeletal system morphogenesis

value: Q14819652
source count: 1
confidence: 0.2
value label: ureteric bud development

value: Q17917742
source count: 1
confidence: 0.2
value label: EYA1

value: Q15978631
source count: 1
confidence: 0.2
value label: Homo sapiens

value: ENSP00000342626
source count: 1
confidence: 0.2

value: ENSP00000373392
source count: 1
confidence: 0.2

value: ENSP00000373394
source count: 1
confidence: 0.2

value: ENSP00000410176
source count: 1
confidence: 0.2

value: ENSP00000303221
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2019-04-08

source: SIX1 mutations cause branchio-oto-renal syndrome by disruption of EYA1-SIX1-DNA complexes
stated in qid: Q24292967
retrieved: 2019-04-08

source: GOA
stated in qid: Q28018111
retrieved: 2018-02-27

source: Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions
stated in qid: Q24313501
retrieved: 2018-02-27

source: Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions
stated in qid: Q24313501
retrieved: 2019-04-08

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-04-08

source: Biochemical and functional characterization of six SIX1 Branchio-oto-renal syndrome mutations
stated in qid: Q24317065
retrieved: 2019-04-08

source: Biochemical and functional characterization of six SIX1 Branchio-oto-renal syndrome mutations
stated in qid: Q24317065
retrieved: 2018-02-27

source: A human homologue of the Drosophila eyes absent gene underlies branchio-oto-renal (BOR) syndrome and identifies a novel gene family
stated in qid: Q24318377
retrieved: 2019-04-08

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2019-11-13

source: Q20641742
stated in qid: Q20641742
retrieved: 2020-05-30

source: Ensembl Release 99
stated in qid: Q83867711

wikidata id: Q21114453
domain: protein
level: standard
html url: https://4ort.xyz/entity/eya-transcriptional-coactivator-and-phosphatase-1-q21114453
markdown url: https://4ort.xyz/entity/eya-transcriptional-coactivator-and-phosphatase-1-q21114453.md
facts url summary: https://4ort.xyz/entity/eya-transcriptional-coactivator-and-phosphatase-1-q21114453/facts.json
facts url standard: https://4ort.xyz/entity/eya-transcriptional-coactivator-and-phosphatase-1-q21114453/facts.json
facts url full: https://4ort.xyz/entity/eya-transcriptional-coactivator-and-phosphatase-1-q21114453/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-04T03:46:40.439057Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T13:58:50.900290+00:00Z