# Extradenticle Dmel_CG8933

> protein found in Drosophila melanogaster

**Wikidata**: [Q29815393](https://www.wikidata.org/wiki/Q29815393)  
**Source**: https://4ort.xyz/entity/extradenticle-dmel-cg8933


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P40427)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40427)
5. [Structure of a DNA-bound Ultrabithorax-Extradenticle homeodomain complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40427)
6. [Transcriptional activation by extradenticle in the Drosophila visceral mesoderm](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40427)
7. [extradenticle, a regulator of homeotic gene activity, is a homolog of the homeobox-containing human proto-oncogene pbx1.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40427)
8. [Synergistic activation of a Drosophila enhancer by HOM/EXD and DPP signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=P40427&geneProductId=UniProtKB:P40427)
9. [Dissecting the functional specificities of two Hox proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P40427&geneProductId=UniProtKB:P40427)
10. [Activity regulation of a Hox protein and a role for the homeodomain in inhibiting transcriptional activation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P40427&geneProductId=UniProtKB:P40427)
11. [Hox and senseless antagonism functions as a molecular switch to regulate EGF secretion in the Drosophila PNS.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P40427&geneProductId=UniProtKB:P40427)
12. [Extradenticle protein is a selective cofactor for the Drosophila homeotics: role of the homeodomain and YPWM amino acid motif in the interaction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40427)
13. [Activity regulation of a Hox protein and a role for the homeodomain in inhibiting transcriptional activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40427)
14. [dorsotonals/homothorax, the Drosophila homologue of meis1, interacts with extradenticle in patterning of the embryonic PNS](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40427)
15. [The Homothorax homeoprotein activates the nuclear localization of another homeoprotein, Extradenticle, and suppresses eye development in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40427)
16. [Nuclear translocation of extradenticle requires homothorax, which encodes an extradenticle-related homeodomain protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40427)
17. [A flexible extension of the Drosophila ultrabithorax homeodomain defines a novel Hox/PBC interaction mode](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40427)
18. [Direct interaction of two homeoproteins, homothorax and extradenticle, is essential for EXD nuclear localization and function.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40427)
19. [A protein interaction map of Drosophila melanogaster](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40427)
20. [Functional Specificity of a Hox Protein Mediated by the Recognition of Minor Groove Structure](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40427)
21. [Hox proteins display a common and ancestral ability to diversify their interaction mode with the PBC class cofactors.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40427)
22. [Analysis of the expression patterns, subcellular localisations and interaction partners of Drosophila proteins using a pigP protein trap library](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40427)
23. [Control of the nuclear localization of Extradenticle by competing nuclear import and export signals](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40427)
24. [Internal regulatory interactions determine DNA binding specificity by a Hox transcription factor.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40427)
25. [Dissecting the functional specificities of two Hox proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40427)
26. [Segment-specific regulation of the Drosophila AP-2 gene during leg and antennal development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40427)
27. [Synergistic activation of a Drosophila enhancer by HOM/EXD and DPP signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40427)
28. [A Hox complex activates and potentiates the Epidermal Growth Factor signaling pathway to specify Drosophila oenocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40427)
29. [Hox and senseless antagonism functions as a molecular switch to regulate EGF secretion in the Drosophila PNS.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40427)
30. [Generation of multiple antagonistic domains along the proximodistal axis during Drosophila leg development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40427)
31. [Functional and regulatory interactions between Hox and extradenticle genes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40427)
32. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P40427&geneProductId=UniProtKB:P40427)
33. [Patterning defects in the primary axonal scaffolds caused by the mutations of the extradenticle and homothorax genes in the embryonic Drosophila brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40427)
34. [Constructing an organ: the Drosophila salivary gland as a model for tube formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40427)
35. [Organ formation in Drosophila: specification and morphogenesis of the salivary gland.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40427)
36. [Tube morphogenesis: closure, but many openings remain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40427)
37. [abdominal A specifies one cell type in Drosophila by regulating one principal target gene.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40427)
38. [Extradenticle and Homothorax Control Adult Muscle Fiber Identity in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40427)
39. ensembl Release 106