# Expanded Dmel_CG4114

> protein found in Drosophila melanogaster

**Wikidata**: [Q29812380](https://www.wikidata.org/wiki/Q29812380)  
**Source**: https://4ort.xyz/entity/expanded-dmel-cg4114


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q07436)
3. Q20641742
4. [Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07436)
5. [The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07436)
6. [The neurofibromatosis-2 homologue, Merlin, and the tumor suppressor expanded function together in Drosophila to regulate cell proliferation and differentiation.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07436)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07436)
8. [The FERM-domain protein Expanded regulates Hippo pathway activity via direct interactions with the transcriptional activator Yorkie](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07436)
9. [Ack promotes tissue growth via phosphorylation and suppression of the Hippo pathway component Expanded](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07436)
10. [Membrane targeting.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07436)
11. [Control of growth and organ size in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07436&geneProductId=UniProtKB:Q07436)
12. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07436&geneProductId=UniProtKB:Q07436)
13. [The neurofibromatosis-2 homologue, Merlin, and the tumor suppressor expanded function together in Drosophila to regulate cell proliferation and differentiation.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07436&geneProductId=UniProtKB:Q07436)
14. [Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07436&geneProductId=UniProtKB:Q07436)
15. [Kibra and Merlin Activate the Hippo Pathway Spatially Distinct from and Independent of Expanded](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07436)
16. [Fat and expanded act in parallel to regulate growth through warts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07436)
17. [Phosphorylation-independent repression of Yorkie in Fat-Hippo signaling.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07436)
18. [Kibra is a regulator of the Salvador/Warts/Hippo signaling network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07436)
19. [Crumbs promotes expanded recognition and degradation by the SCF(Slimb/β-TrCP) ubiquitin ligase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07436)
20. [The Drosophila tumor suppressors Expanded and Merlin differentially regulate cell cycle exit, apoptosis, and Wingless signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07436)
21. [The tumor suppressors Merlin and Expanded function cooperatively to modulate receptor endocytosis and signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07436)
22. [The Hippo pathway polarizes the actin cytoskeleton during collective migration of Drosophila border cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07436)
23. [The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07436)
24. [A large-scale in vivo RNAi screen to identify genes involved in Notch-mediated follicle cell differentiation and cell cycle switches](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07436)
25. [Vamana Couples Fat Signaling to the Hippo Pathway](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07436&geneProductId=UniProtKB:Q07436)
26. [The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07436&geneProductId=UniProtKB:Q07436)
27. [Fat and expanded act in parallel to regulate growth through warts](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07436&geneProductId=UniProtKB:Q07436)
28. [The Hippo tumor-suppressor pathway regulates apical-domain size in parallel to tissue growth](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07436&geneProductId=UniProtKB:Q07436)
29. [The FERM-domain protein Expanded regulates Hippo pathway activity via direct interactions with the transcriptional activator Yorkie](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07436&geneProductId=UniProtKB:Q07436)
30. [Genes affecting cell competition in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07436&geneProductId=UniProtKB:Q07436)
31. [The Drosophila tumor suppressors Expanded and Merlin differentially regulate cell cycle exit, apoptosis, and Wingless signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07436&geneProductId=UniProtKB:Q07436)
32. [Zyxin Links Fat Signaling to the Hippo Pathway](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07436&geneProductId=UniProtKB:Q07436)
33. [Phosphorylation-independent repression of Yorkie in Fat-Hippo signaling.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07436&geneProductId=UniProtKB:Q07436)
34. [The WW domain protein Kibra acts upstream of Hippo in Drosophila.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07436)
35. [The Hippo tumor-suppressor pathway regulates apical-domain size in parallel to tissue growth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07436)
36. [The fat cadherin acts through the hippo tumor-suppressor pathway to regulate tissue size.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07436)
37. [In vivo regulation of Yorkie phosphorylation and localization.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07436)
38. [Genes affecting cell competition in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07436)
39. [Zyxin Links Fat Signaling to the Hippo Pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07436)
40. ensembl Release 106