# Eukaryotic translation initiation factor 4A3

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21131475](https://www.wikidata.org/wiki/Q21131475)  
**Source**: https://4ort.xyz/entity/eukaryotic-translation-initiation-factor-4a3-q21131475


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P38919)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
5. [Eukaryotic Translation Initiation Factor 4AIII (eIF4AIII) Is Functionally Distinct from eIF4AI and eIF4AII](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
6. [SKAR Links Pre-mRNA Splicing to mTOR/S6K1-Mediated Enhanced Translation Efficiency of Spliced mRNAs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
7. [Human CWC22 escorts the helicase eIF4AIII to spliceosomes and promotes exon junction complex assembly](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
8. [mRNA export through an additional cap-binding complex consisting of NCBP1 and NCBP3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
9. [NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
10. [TRAP150 activates pre-mRNA splicing and promotes nuclear mRNA degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
11. [Insights into the recruitment of the NMD machinery from the crystal structure of a core EJC-UPF3b complex.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
12. [The Crystal Structure of the Exon Junction Complex Reveals How It Maintains a Stable Grip on mRNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
13. [An eIF4AIII-containing complex required for mRNA localization and nonsense-mediated mRNA decay](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
14. [Human spliceosomal protein CWC22 plays a role in coupling splicing to exon junction complex deposition and nonsense-mediated decay](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
15. [eIF4G is required for the pioneer round of translation in mammalian cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
16. [The exon junction core complex is locked onto RNA by inhibition of eIF4AIII ATPase activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
17. [Dynamic Protein-Protein Interaction Wiring of the Human Spliceosome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
18. [eIF4A3 is a novel component of the exon junction complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
19. [SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
20. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
21. [Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
22. [The Hierarchy of Exon-Junction Complex Assembly by the Spliceosome Explains Key Features of Mammalian Nonsense-Mediated mRNA Decay](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
23. [Human eIF4AIII interacts with an eIF4G-like partner, NOM1, revealing an evolutionarily conserved function outside the exon junction complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
24. [LuTHy: a double‐readout bioluminescence‐based two‐hybrid technology for quantitative mapping of protein–protein interactions in mammalian cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
25. [The cryo-EM structure of the UPF–EJC complex shows UPF1 poised toward the RNA 3′ end](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
26. [A Proteome-Scale Map of the Human Interactome Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
27. [Disassembly of Exon Junction Complexes by PYM](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
28. [Exon-Junction Complex Components Specify Distinct Routes of Nonsense-Mediated mRNA Decay with Differential Cofactor Requirements](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
29. [The Cellular EJC Interactome Reveals Higher-Order mRNP Structure and an EJC-SR Protein Nexus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
30. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P38919&geneProductId=UniProtKB:P38919)
31. [Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P38919&geneProductId=UniProtKB:P38919)
32. [The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts](http://www.ebi.ac.uk/QuickGO/annotations?protein=P38919&geneProductId=UniProtKB:P38919)
33. [The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
34. [Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
35. [Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
36. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P38919&geneProductId=UniProtKB:P38919)
37. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
38. [Structure of a human catalytic step I spliceosome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
39. [A Noncoding Expansion in EIF4A3 Causes Richieri-Costa-Pereira Syndrome, a Craniofacial Disorder Associated with Limb Defects](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38919)
40. [Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P38919&geneProductId=UniProtKB:P38919)
41. ensembl Release 93
42. Transporter Classification database