# Eukaryotic translation initiation factor 2B subunit epsilon

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21110118](https://www.wikidata.org/wiki/Q21110118)  
**Source**: https://4ort.xyz/entity/eukaryotic-translation-initiation-factor-2b-subunit-epsilon-q21110118


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q13144)
3. Q20641742
4. [Cloning and characterization of cDNAs encoding the epsilon-subunit of eukaryotic initiation factor-2B from rabbit and human](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13144&geneProductId=UniProtKB:Q13144)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13144&geneProductId=UniProtKB:Q13144)
6. [An efficient mammalian cell-free translation system supplemented with translation factors](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13144&geneProductId=UniProtKB:Q13144)
7. [Decreased guanine nucleotide exchange factor activity in eIF2B-mutated patients](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13144&geneProductId=UniProtKB:Q13144)
8. [Characterization of the mammalian initiation factor eIF2B complex as a GDP dissociation stimulator protein](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13144&geneProductId=UniProtKB:Q13144)
9. [Mutations linked to leukoencephalopathy with vanishing white matter impair the function of the eukaryotic initiation factor 2B complex in diverse ways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13144)
10. [A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of axin and beta-catenin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13144)
11. [Cloning and characterization of cDNAs encoding the epsilon-subunit of eukaryotic initiation factor-2B from rabbit and human](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13144)
12. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13144)
13. [An efficient mammalian cell-free translation system supplemented with translation factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13144)
14. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13144)
15. [Decreased guanine nucleotide exchange factor activity in eIF2B-mutated patients](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13144)
16. [Characterization of the mammalian initiation factor eIF2B complex as a GDP dissociation stimulator protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13144)
17. [Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13144)
18. [Mutations linked to leukoencephalopathy with vanishing white matter impair the function of the eukaryotic initiation factor 2B complex in diverse ways](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13144&geneProductId=UniProtKB:Q13144)
19. [EIF2B5 mutations compromise GFAP+ astrocyte generation in vanishing white matter leukodystrophy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13144)
20. [A severe variant of childhood ataxia with central hypomyelination/vanishing white matter leukoencephalopathy related to EIF21B5 mutation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13144)
21. [Heightened stress response in primary fibroblasts expressing mutant eIF2B genes from CACH/VWM leukodystrophy patients](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13144)
22. [Screening for known mutations in EIF2Bgenes in a large panel of patients with premature ovarian failure](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13144)
23. [eIF2B-related disorders: antenatal onset and involvement of multiple organs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13144)
24. [The life and death of oligodendrocytes in vanishing white matter disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13144)
25. [T-cell activation leads to rapid stimulation of translation initiation factor eIF2B and inactivation of glycogen synthase kinase-3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13144)
26. ensembl Release 93