# Eukaryotic translation initiation factor 2B subunit beta

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21110110](https://www.wikidata.org/wiki/Q21110110)  
**Source**: https://4ort.xyz/entity/eukaryotic-translation-initiation-factor-2b-subunit-beta-q21110110


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P49770)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49770)
5. [An efficient mammalian cell-free translation system supplemented with translation factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49770)
6. [Decreased guanine nucleotide exchange factor activity in eIF2B-mutated patients](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49770)
7. [Characterization of the mammalian initiation factor eIF2B complex as a GDP dissociation stimulator protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49770)
8. [Mutations linked to leukoencephalopathy with vanishing white matter impair the function of the eukaryotic initiation factor 2B complex in diverse ways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49770)
9. [Widespread macromolecular interaction perturbations in human genetic disorders](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49770)
10. [Next-generation sequencing to generate interactome datasets](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49770)
11. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49770)
12. [A severe variant of childhood ataxia with central hypomyelination/vanishing white matter leukoencephalopathy related to EIF21B5 mutation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49770)
13. [Identification of ten novel mutations in patients with eIF2B-related disorders](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49770)
14. [Screening for known mutations in EIF2Bgenes in a large panel of patients with premature ovarian failure](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49770)
15. [eIF2B-related disorders: antenatal onset and involvement of multiple organs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49770)
16. [The life and death of oligodendrocytes in vanishing white matter disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49770)
17. [T-cell activation leads to rapid stimulation of translation initiation factor eIF2B and inactivation of glycogen synthase kinase-3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49770)
18. Ensembl Release 99