# ETS proto-oncogene 1, transcription factor

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21116585](https://www.wikidata.org/wiki/Q21116585)  
**Source**: https://4ort.xyz/entity/ets-proto-oncogene-1-transcription-factor-q21116585


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P14921)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921)
5. [Sp100 interacts with ETS-1 and stimulates its transcriptional activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921)
6. [SP100 expression modulates ETS1 transcriptional activity and inhibits cell invasion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921)
7. [EAP1/Daxx interacts with ETS1 and represses transcriptional activation of ETS1 target genes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921)
8. [Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921)
9. [ETS-dependent p16INK4a and p21waf1/cip1 gene expression upon endothelin-1 stimulation in malignant versus and non-malignant proximal tubule cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921)
10. [Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921)
11. [Differential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineages](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921)
12. [Cooperative interaction between ETS1 and GFI1 transcription factors in the repression of Bax gene expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921)
13. [A Comprehensive Resource of Interacting Protein Regions for Refining Human Transcription Factor Networks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921)
14. [Toward an understanding of the protein interaction network of the human liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921)
15. [Physical and functional interactions between hematopoietic cell-specific ETS transcription factors and homeodomain proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921)
16. [Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921)
17. [Constitutive activation of the ETS‐1‐miR‐222 circuitry in metastatic melanoma](http://www.ebi.ac.uk/QuickGO/annotations?protein=P14921&geneProductId=UniProtKB:P14921)
18. [Basal transcription of the mouse sarco(endo)plasmic reticulum Ca2+-ATPase type 3 gene in endothelial cells is controlled by Ets-1 and Sp1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921)
19. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P14921&geneProductId=UniProtKB:P14921)
20. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?protein=P14921&geneProductId=UniProtKB:P14921)
21. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P14921&geneProductId=UniProtKB:P14921)
22. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921)
23. [Constitutive activation of the ETS‐1‐miR‐222 circuitry in metastatic melanoma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921)
24. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921)
25. [EAP1/Daxx interacts with ETS1 and represses transcriptional activation of ETS1 target genes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P14921&geneProductId=UniProtKB:P14921)
26. [A variant form of ETS1 induces apoptosis in human colon cancer cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P14921&geneProductId=UniProtKB:P14921)
27. [SP100 expression modulates ETS1 transcriptional activity and inhibits cell invasion](http://www.ebi.ac.uk/QuickGO/annotations?protein=P14921&geneProductId=UniProtKB:P14921)
28. [Sp100 interacts with ETS-1 and stimulates its transcriptional activity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P14921&geneProductId=UniProtKB:P14921)
29. [MafB is an interaction partner and repressor of Ets-1 that inhibits erythroid differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921)
30. [ETS1 suppresses tumorigenicity of human colon cancer cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P14921&geneProductId=UniProtKB:P14921)
31. [SP100 inhibits ETS1 activity in primary endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921)
32. [Reciprocal expression of human ETS1 and ETS2 genes during T-cell activation: regulatory role for the protooncogene ETS1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921)
33. [Tenascin-C upregulation by transforming growth factor-beta in human dermal fibroblasts involves Smad3, Sp1, and Ets1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921)
34. [Endothelial enriched microRNAs regulate angiotensin II-induced endothelial inflammation and migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921)
35. [miR-200b Targets Ets-1 and Is Down-regulated by Hypoxia to Induce Angiogenic Response of Endothelial Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14921)
36. Ensembl Release 99
37. UMLS 2023