# ERCC excision repair 3, TFIIH core complex helicase subunit

> mammalian protein found in Homo sapiens

**Wikidata**: [Q426194](https://www.wikidata.org/wiki/Q426194)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/XPB)  
**Source**: https://4ort.xyz/entity/ercc-excision-repair-3-tfiih-core-complex-helicase-subunit


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P19447)
3. Q20641742
4. [Distinct roles for the XPB/p52 and XPD/p44 subcomplexes of TFIIH in damaged DNA opening during nucleotide excision repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19447)
5. [Distinct regions of MAT1 regulate cdk7 kinase and TFIIH transcription activities](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19447)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19447)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19447&geneProductId=UniProtKB:P19447)
8. [Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19447)
9. [A 3' --> 5' XPB helicase defect in repair/transcription factor TFIIH of xeroderma pigmentosum group B affects both DNA repair and transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19447)
10. [Interactions involving the human RNA polymerase II transcription/nucleotide excision repair complex TFIIH, the nucleotide excision repair protein XPG, and Cockayne syndrome group B (CSB) protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19447)
11. [A 3' --> 5' XPB helicase defect in repair/transcription factor TFIIH of xeroderma pigmentosum group B affects both DNA repair and transcription](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19447&geneProductId=UniProtKB:P19447)
12. [Distinct roles for the XPB/p52 and XPD/p44 subcomplexes of TFIIH in damaged DNA opening during nucleotide excision repair](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19447&geneProductId=UniProtKB:P19447)
13. [A presumed DNA helicase encoded by ERCC-3 is involved in the human repair disorders xeroderma pigmentosum and Cockayne's syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19447)
14. [The XPB subunit of repair/transcription factor TFIIH directly interacts with SUG1, a subunit of the 26S proteasome and putative transcription factor](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19447&geneProductId=UniProtKB:P19447)
15. [Detection and identification of transcription factors as interaction partners of alien in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19447)
16. [Human cyclin-dependent kinase-activating kinase exists in three distinct complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19447)
17. [The XPB subunit of repair/transcription factor TFIIH directly interacts with SUG1, a subunit of the 26S proteasome and putative transcription factor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19447)
18. [Transcription factor IIE binds preferentially to RNA polymerase IIa and recruits TFIIH: a model for promoter clearance](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19447)
19. [p53 modulation of TFIIH–associated nucleotide excision repair activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19447)
20. [Structural basis for group A trichothiodystrophy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19447)
21. [A human interactome in three quantitative dimensions organized by stoichiometries and abundances](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19447)
22. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19447)
23. [Near-atomic resolution visualization of human transcription promoter opening](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19447)
24. [Toward an understanding of the protein interaction network of the human liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19447)
25. [Dynamic interaction of TTDA with TFIIH is stabilized by nucleotide excision repair in living cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19447)
26. [The xeroderma pigmentosum group C protein complex XPC-HR23B plays an important role in the recruitment of transcription factor IIH to damaged DNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19447)
27. [Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19447&geneProductId=UniProtKB:P19447)
28. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19447)
29. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19447&geneProductId=UniProtKB:P19447)
30. [p53 modulation of TFIIH–associated nucleotide excision repair activity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19447&geneProductId=UniProtKB:P19447)
31. [Human cyclin-dependent kinase-activating kinase exists in three distinct complexes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19447&geneProductId=UniProtKB:P19447)
32. [Influence of XPB helicase on recruitment and redistribution of nucleotide excision repair proteins at sites of UV-induced DNA damage](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19447&geneProductId=UniProtKB:P19447)
33. [Isolation and characterization of two human transcription factor IIH (TFIIH)-related complexes: ERCC2/CAK and TFIIH](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19447&geneProductId=UniProtKB:P19447)
34. [DNA nucleotide excision repair-dependent signaling to checkpoint activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19447)
35. [The XPB and XPD DNA helicases are components of the p53-mediated apoptosis pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19447)
36. [The role of XPB in cell apoptosis and viability and its relationship with p53, p21(waf1/cip1) and c-myc in hepatoma cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19447)
37. [Trichothiodystrophy, a transcription syndrome](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19447&geneProductId=UniProtKB:P19447)
38. [Genetic susceptibility of newborn daughters to oxidative stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19447)
39. [Influence of XPB helicase on recruitment and redistribution of nucleotide excision repair proteins at sites of UV-induced DNA damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19447)
40. [Isolation and characterization of two human transcription factor IIH (TFIIH)-related complexes: ERCC2/CAK and TFIIH](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19447)
41. [Trichothiodystrophy, a transcription syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19447)
42. [DNA nucleotide excision repair-dependent signaling to checkpoint activation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19447&geneProductId=UniProtKB:P19447)
43. Ensembl Release 99
44. Identifiers.org