# ERCC excision repair 1, endonuclease non-catalytic subunit

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21110095](https://www.wikidata.org/wiki/Q21110095)  
**Source**: https://4ort.xyz/entity/ercc-excision-repair-1-endonuclease-non-catalytic-subunit


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P07992)
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/K7EK97)
4. Q20641742
5. [Analysis of the XPA and ssDNA-binding surfaces on the central domain of human ERCC1 reveals evidence for subfunctionalization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992)
6. [Crystal structure and DNA binding functions of ERCC1, a subunit of the DNA structure-specific endonuclease XPF-ERCC1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07992&geneProductId=UniProtKB:P07992)
7. [Analysis of the XPA and ssDNA-binding surfaces on the central domain of human ERCC1 reveals evidence for subfunctionalization](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07992&geneProductId=UniProtKB:P07992)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07992&geneProductId=UniProtKB:P07992)
9. [Purification and characterization of the XPF-ERCC1 complex of human DNA repair excision nuclease](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07992&geneProductId=UniProtKB:P07992)
10. [Mapping of interaction domains between human repair proteins ERCC1 and XPF](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992)
11. [Formation of a ternary complex by human XPA, ERCC1, and ERCC4(XPF) excision repair proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992)
12. [Reconstitution of human excision nuclease with recombinant XPF-ERCC1 complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992)
13. [ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992)
14. [XPA versus ERCC1 as chemosensitising agents to cisplatin and mitomycin C in prostate cancer cells: role of ERCC1 in homologous recombination repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992)
15. [Purification and characterization of the XPF-ERCC1 complex of human DNA repair excision nuclease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992)
16. [Functional and physical interactions between ERCC1 and MSH2 complexes for resistance to cis-diamminedichloroplatinum(II) in mammalian cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992)
17. [Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992)
18. [Importance of EGFR/ERCC1 interaction following radiation-induced DNA damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992)
19. [The structure of the human ERCC1/XPF interaction domains reveals a complementary role for the two proteins in nucleotide excision repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992)
20. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992)
21. [A novel cytoplasmic GTPase XAB1 interacts with DNA repair protein XPA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992)
22. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992)
23. [Recognition of helical kinks by xeroderma pigmentosum group A protein triggers DNA excision repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992)
24. [Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992)
25. [Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992)
26. [XPF with mutations in its conserved nuclease domain is defective in DNA repair but functions in TRF2-mediated telomere shortening](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992)
27. [Human XPF controls TRF2 and telomere length maintenance through distinctive mechanisms](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992)
28. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992)
29. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:K7EK97)
30. [Physical and functional interaction between the XPF/ERCC1 endonuclease and hRad52](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992)
31. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992)
32. [Crystal structure and DNA binding functions of ERCC1, a subunit of the DNA structure-specific endonuclease XPF-ERCC1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992)
33. [XPF with mutations in its conserved nuclease domain is defective in DNA repair but functions in TRF2-mediated telomere shortening](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07992&geneProductId=UniProtKB:P07992)
34. [ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07992&geneProductId=UniProtKB:P07992)
35. [Domain mapping of the DNA binding, endonuclease, and ERCC1 binding properties of the human DNA repair protein XPF](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07992&geneProductId=UniProtKB:P07992)
36. [Evolution and mutagenesis of the mammalian excision repair gene ERCC-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992)
37. [Domain mapping of the DNA binding, endonuclease, and ERCC1 binding properties of the human DNA repair protein XPF](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992)
38. [The structure-specific endonuclease Ercc1-Xpf is required for targeted gene replacement in embryonic stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992)
39. [Genetic susceptibility of newborn daughters to oxidative stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992)
40. [In vitro repair of oxidative DNA damage by human nucleotide excision repair system: Possible explanation for neurodegeneration in Xeroderma pigmentosum patients](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992)
41. [Mutational analysis of the human nucleotide excision repair gene ERCC1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07992&geneProductId=UniProtKB:P07992)
42. [USP45 deubiquitylase controls ERCC1-XPF endonuclease-mediated DNA damage responses](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992)
43. [Human DNA repair excision nuclease. Analysis of the roles of the subunits involved in dual incisions by using anti-XPG and anti-ERCC1 antibodies](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07992&geneProductId=UniProtKB:P07992)
44. [Human DNA repair excision nuclease. Analysis of the roles of the subunits involved in dual incisions by using anti-XPG and anti-ERCC1 antibodies](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992)
45. [Mutational analysis of the human nucleotide excision repair gene ERCC1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992)
46. Ensembl Release 99
47. UMLS 2023