# EPM2A glucan phosphatase, laforin

> mammalian protein found in Homo sapiens

**Wikidata**: [Q22679436](https://www.wikidata.org/wiki/Q22679436)  
**Source**: https://4ort.xyz/entity/epm2a-glucan-phosphatase-laforin


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O95278)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95278)
5. [Dimeric quaternary structure of human laforin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95278)
6. [Early-onset Lafora body disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95278)
7. [Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95278)
8. [Insights into Lafora disease: malin is an E3 ubiquitin ligase that ubiquitinates and promotes the degradation of laforin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95278)
9. [The Lafora disease gene product laforin interacts with HIRIP5, a phylogenetically conserved protein containing a NifU-like domain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95278)
10. [Structural mechanism of laforin function in glycogen dephosphorylation and lafora disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95278)
11. [Lafora progressive myoclonus epilepsy: NHLRC1 mutations affect glycogen metabolism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95278)
12. [Laforin, the dual-phosphatase responsible for Lafora disease, interacts with R5 (PTG), a regulatory subunit of protein phosphatase-1 that enhances glycogen accumulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95278)
13. [A Unique Carbohydrate Binding Domain Targets the Lafora Disease Phosphatase to Glycogen](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95278)
14. [Laforin, defective in the progressive myoclonus epilepsy of Lafora type, is a dual-specificity phosphatase associated with polyribosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95278)
15. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O95278&geneProductId=UniProtKB:O95278)
16. [Modulation of functional properties of laforin phosphatase by alternative splicing reveals a novel mechanism for the EPM2A gene in Lafora progressive myoclonus epilepsy](http://www.ebi.ac.uk/QuickGO/annotations?protein=O95278&geneProductId=UniProtKB:O95278)
17. [Dimeric quaternary structure of human laforin](http://www.ebi.ac.uk/QuickGO/annotations?protein=O95278&geneProductId=UniProtKB:O95278)
18. [Laforin, a dual specificity phosphatase that dephosphorylates complex carbohydrates](http://www.ebi.ac.uk/QuickGO/annotations?protein=O95278&geneProductId=UniProtKB:O95278)
19. [Laforin, a dual specificity phosphatase that dephosphorylates complex carbohydrates](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95278)
20. [A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95278)
21. [A novel protein tyrosine phosphatase gene is mutated in progressive myoclonus epilepsy of the Lafora type (EPM2)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95278)
22. Ensembl Release 99