Epithelial mitogen
type: Thing
description: mammalian protein found in Mus musculus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P361
  value: membrane protein
additional property: PropertyValue
  property ID: P361
  value: EGF-like domain, protein family
additional property: PropertyValue
  property ID: P361
  value: EGF-like, conserved site, protein family
additional property: PropertyValue
  property ID: P527
  value: EGF-like, conserved site
additional property: PropertyValue
  property ID: P527
  value: EGF-like domain
additional property: PropertyValue
  property ID: P637
  value: NP_444317
additional property: PropertyValue
  property ID: P680
  value: epidermal growth factor receptor binding
additional property: PropertyValue
  property ID: P680
  value: growth factor activity
additional property: PropertyValue
  property ID: P680
  value: epidermal growth factor receptor binding
additional property: PropertyValue
  property ID: P681
  value: integral component of membrane
additional property: PropertyValue
  property ID: P681
  value: integral component of plasma membrane
additional property: PropertyValue
  property ID: P681
  value: membrane
additional property: PropertyValue
  property ID: P682
  value: positive regulation of epidermal growth factor-activated receptor activity
additional property: PropertyValue
  property ID: P682
  value: positive regulation of mitotic nuclear division
additional property: PropertyValue
  property ID: P682
  value: positive regulation of MAP kinase activity
additional property: PropertyValue
  property ID: P702
  value: Epgn
additional property: PropertyValue
  property ID: P703
  value: house mouse
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000046987
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000144500
confidence:
  popularity graph score:
    score: 0.001
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 9
      unique citations norm: 0.004
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 9
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: Q924X1
    source count: 1
    confidence: 0.2
  P361:
    value: Q423042
    source count: 1
    confidence: 0.2
    value label: membrane protein
  P361:
    value: Q83134378
    source count: 1
    confidence: 0.2
    value label: EGF-like domain, protein family
  P361:
    value: Q95352453
    source count: 1
    confidence: 0.2
    value label: EGF-like, conserved site, protein family
  P527:
    value: Q24786224
    source count: 1
    confidence: 0.2
    value label: EGF-like, conserved site
  P527:
    value: Q24723491
    source count: 1
    confidence: 0.2
    value label: EGF-like domain
  P637:
    value: NP_444317
    source count: 1
    confidence: 0.2
  P680:
    value: Q14864679
    source count: 3
    confidence: 0.6
    value label: epidermal growth factor receptor binding
  P680:
    value: Q14820601
    source count: 5
    confidence: 1.0
    value label: growth factor activity
  P680:
    value: Q14864679
    source count: 4
    confidence: 0.8
    value label: epidermal growth factor receptor binding
  P680:
    value: Q14820601
    source count: 6
    confidence: 1.0
    value label: growth factor activity
  P681:
    value: Q14327652
    source count: 1
    confidence: 0.2
    value label: integral component of membrane
  P681:
    value: Q14859540
    source count: 3
    confidence: 0.6
    value label: integral component of plasma membrane
  P681:
    value: Q14349455
    source count: 1
    confidence: 0.2
    value label: membrane
  P681:
    value: Q3824358
    source count: 1
    confidence: 0.2
    value label: intracellular anatomical structure
  P681:
    value: Q1385443
    source count: 1
    confidence: 0.2
    value label: extracellular space
  P682:
    value: Q14864687
    source count: 3
    confidence: 0.6
    value label: positive regulation of epidermal growth factor-activated receptor activity
  P682:
    value: Q14758946
    source count: 3
    confidence: 0.6
    value label: positive regulation of mitotic nuclear division
  P682:
    value: Q14864686
    source count: 3
    confidence: 0.6
    value label: positive regulation of MAP kinase activity
  P682:
    value: Q539568
    source count: 3
    confidence: 0.6
    value label: angiogenesis
  P682:
    value: Q14633891
    source count: 2
    confidence: 0.4
    value label: positive regulation of cell population proliferation
  P702:
    value: Q18265166
    source count: 1
    confidence: 0.2
    value label: Epgn
  P703:
    value: Q83310
    source count: 1
    confidence: 0.2
    value label: house mouse
  P705:
    value: ENSMUSP00000046987
    source count: 1
    confidence: 0.2

value: ENSMUSP00000144500
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2018-03-27

source: Cloning and biological activity of epigen, a novel member of the epidermal growth factor superfamily
stated in qid: Q24291006
retrieved: 2018-03-27

source: GOA
stated in qid: Q28018111
retrieved: 2019-02-14

source: Cloning and biological activity of epigen, a novel member of the epidermal growth factor superfamily
stated in qid: Q24291006
retrieved: 2019-02-14

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-02-14

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2022-05-25

source: Q20641742
stated in qid: Q20641742
retrieved: 2022-03-20

source: ensembl Release 106
stated in qid: Q111699881

wikidata id: Q21496343
domain: protein
level: standard
html url: https://4ort.xyz/entity/epithelial-mitogen-q21496343
markdown url: https://4ort.xyz/entity/epithelial-mitogen-q21496343.md
facts url summary: https://4ort.xyz/entity/epithelial-mitogen-q21496343/facts.json
facts url standard: https://4ort.xyz/entity/epithelial-mitogen-q21496343/facts.json
facts url full: https://4ort.xyz/entity/epithelial-mitogen-q21496343/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-24T10:06:09.302088Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T15:12:15.838670+00:00Z