epithelial cell adhesion molecule
type: Thing
alternate name: adenocarcinoma-associated antigen
alternate name: hEGP314
alternate name: Epithelial cell surface antigen
alternate name: tumor-associated calcium signal transducer 1
alternate name: EGP
alternate name: EGP314
alternate name: cell surface glycoprotein Trop-1
alternate name: KS 1/4 antigen
alternate name: human epithelial glycoprotein-2
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P352
  value: P16422
additional property: PropertyValue
  property ID: P361
  value: Thyroglobulin type-1 superfamily
additional property: PropertyValue
  property ID: P361
  value: Thyroglobulin type-1, protein family
additional property: PropertyValue
  property ID: P486
  value: D000071858
additional property: PropertyValue
  property ID: P527
  value: Thyroglobulin type-1
additional property: PropertyValue
  property ID: P637
  value: NP_002345
additional property: PropertyValue
  property ID: P638
  value: 4MZV
additional property: PropertyValue
  property ID: P646
  value: /m/03gwry5
additional property: PropertyValue
  property ID: P672
  value: D12.776.395.550.200.263
additional property: PropertyValue
  property ID: P672
  value: D12.776.543.550.200.263
additional property: PropertyValue
  property ID: P672
  value: D23.050.285.357
additional property: PropertyValue
  property ID: P680
  value: protein-containing complex binding
additional property: PropertyValue
  property ID: P680
  value: protein binding
additional property: PropertyValue
  property ID: P680
  value: cadherin binding involved in cell-cell adhesion
additional property: PropertyValue
  property ID: P681
  value: integral component of membrane
additional property: PropertyValue
  property ID: P681
  value: lateral plasma membrane
additional property: PropertyValue
  property ID: P681
  value: membrane
additional property: PropertyValue
  property ID: P682
  value: ureteric bud development
additional property: PropertyValue
  property ID: P682
  value: positive regulation of cell motility
additional property: PropertyValue
  property ID: P682
  value: negative regulation of cell-cell adhesion mediated by cadherin
additional property: PropertyValue
  property ID: P692
  value: PBB GE TACSTD1 201839 s at fs.png
additional property: PropertyValue
  property ID: P702
  value: EPCAM
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P705
  value: ENSP00000263735
additional property: PropertyValue
  property ID: P705
  value: ENSP00000385476
additional property: PropertyValue
  property ID: P705
  value: ENSP00000389028
additional property: PropertyValue
  property ID: P2892
  value: C1704265
additional property: PropertyValue
  property ID: P6366
  value: 2776677690
additional property: PropertyValue
  property ID: P10283
  value: C2776677690
confidence:
  popularity graph score:
    score: 0.009
    score pct: 1
    tier: established
    components:
      sitelinks: 7
      sitelinks norm: 0.017
      unique citations: 24
      unique citations norm: 0.009
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 7
  unique citations: 24
  monthly pageviews: 0
  yearly pageviews: 187
  pageview trend:
    m: 2026-06
    v: 116
  pageview trend:
    m: 2026-05
    v: 13
  pageview trend:
    m: 2026-05
    v: 7
  pageview trend:
    m: 2026-05
    v: 4
  pageview trend:
    m: 2026-04
    v: 45
  pageview trend:
    m: 2026-04
    v: 1
  pageview trend:
    m: 2026-04
    v: 1
  popularity:
    sitelinks: 7
    max: 423
    pct: 1.7
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: P16422
    source count: 1
    confidence: 0.2
  P361:
    value: Q41797953
    source count: 1
    confidence: 0.2
    value label: Thyroglobulin type-1 superfamily
  P361:
    value: Q83136569
    source count: 1
    confidence: 0.2
    value label: Thyroglobulin type-1, protein family
  P486:
    value: D000071858
    source count: 0
    confidence: 0.0
  P527:
    value: Q24738913
    source count: 1
    confidence: 0.2
    value label: Thyroglobulin type-1
  P637:
    value: NP_002345
    source count: 1
    confidence: 0.2
  P638:
    value: 4MZV
    source count: 1
    confidence: 0.2
  P646:
    value: /m/03gwry5
    source count: 0
    confidence: 0.0
  P672:
    value: D12.776.395.550.200.263
    source count: 0
    confidence: 0.0
  P672:
    value: D12.776.543.550.200.263
    source count: 0
    confidence: 0.0
  P672:
    value: D23.050.285.357
    source count: 0
    confidence: 0.0
  P672:
    value: D23.050.301.350.263
    source count: 0
    confidence: 0.0
  P672:
    value: D09.400.430.890.200.263
    source count: 0
    confidence: 0.0

value: Q22312857
source count: 2
confidence: 0.4
value label: protein-containing complex binding

value: Q167149
source count: 1
confidence: 0.2
value label: protein binding

value: Q22312562
source count: 2
confidence: 0.4
value label: cadherin binding involved in cell-cell adhesion

value: Q14327652
source count: 2
confidence: 0.4
value label: integral component of membrane

value: Q14876816
source count: 3
confidence: 0.6
value label: lateral plasma membrane

value: Q14349455
source count: 1
confidence: 0.2
value label: membrane

value: Q14883308
source count: 3
confidence: 0.6
value label: bicellular tight junction

value: Q29548
source count: 7
confidence: 1.0
value label: plasma membrane

value: Q14819652
source count: 1
confidence: 0.2
value label: ureteric bud development

value: Q14860562
source count: 1
confidence: 0.2
value label: positive regulation of cell motility

value: Q21113767
source count: 1
confidence: 0.2
value label: negative regulation of cell-cell adhesion mediated by cadherin

value: Q14885853
source count: 1
confidence: 0.2
value label: signal transduction involved in regulation of gene expression

value: Q14599533
source count: 1
confidence: 0.2
value label: negative regulation of apoptotic process

value: PBB GE TACSTD1 201839 s at fs.png
source count: 0
confidence: 0.0

value: Q18028744
source count: 1
confidence: 0.2
value label: EPCAM

value: Q15978631
source count: 1
confidence: 0.2
value label: Homo sapiens

value: ENSP00000263735
source count: 1
confidence: 0.2

value: ENSP00000385476
source count: 1
confidence: 0.2

value: ENSP00000389028
source count: 1
confidence: 0.2

value: ENSP00000410675
source count: 1
confidence: 0.2

value: C1704265
source count: 1
confidence: 0.2

value: 2776677690
source count: 0
confidence: 0.0

value: C2776677690
source count: 1
confidence: 0.2

source: Nuclear signalling by tumour-associated antigen EpCAM
stated in qid: Q24315870
retrieved: 2017-09-26

source: Nuclear signalling by tumour-associated antigen EpCAM
stated in qid: Q24315870
retrieved: 2019-04-08

source: The cell-cell adhesion molecule EpCAM interacts directly with the tight junction protein claudin-7
stated in qid: Q24311535
retrieved: 2019-04-08

source: GOA
stated in qid: Q28018111
retrieved: 2019-04-08

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-04-08

source: GOA
stated in qid: Q28018111
retrieved: 2017-09-26

source: The cell-cell adhesion molecule EpCAM interacts directly with the tight junction protein claudin-7
stated in qid: Q24311535
retrieved: 2017-09-26

source: A murine cDNA encodes a pan-epithelial glycoprotein that is also expressed on plasma cells
stated in qid: Q28116984
retrieved: 2019-04-08

source: Characterization of epithelial cell adhesion molecule as a surface marker on undifferentiated human embryonic stem cells
stated in qid: Q24319023
retrieved: 2019-04-08

source: The carcinoma-associated antigen EpCAM upregulates c-myc and induces cell proliferation
stated in qid: Q24296763
retrieved: 2019-04-08

source: Spatial and temporal expression patterns of the epithelial cell adhesion molecule (EpCAM/EGP-2) in developing and adult kidneys
stated in qid: Q24300932
retrieved: 2019-04-08

source: Proteomic analysis of podocyte exosome-enriched fraction from normal human urine
stated in qid: Q24313258
retrieved: 2017-09-26

source: Large-scale proteomics and phosphoproteomics of urinary exosomes
stated in qid: Q24321631
retrieved: 2017-09-26

source: Intestinal epithelial cells secrete exosome-like vesicles
stated in qid: Q24291534
retrieved: 2017-09-26

source: Large-scale proteomics and phosphoproteomics of urinary exosomes
stated in qid: Q24321631
retrieved: 2019-04-08

source: Intestinal epithelial cells secrete exosome-like vesicles
stated in qid: Q24291534
retrieved: 2019-04-08

source: Epithelial Cell Adhesion Molecule (Ep-CAM) Modulates Cell–Cell Interactions Mediated by Classic Cadherins
stated in qid: Q24309815
retrieved: 2019-04-08

source: The tumour-associated antigen EpCAM upregulates the fatty acid binding protein E-FABP
stated in qid: Q24304077
retrieved: 2019-04-08

source: OpenAlex
stated in qid: Q107507571
retrieved: 2022-01-26

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2019-11-13

source: Q20641742
stated in qid: Q20641742
retrieved: 2020-05-30

source: UMLS 2023
stated in qid: Q118645236
retrieved: 2023-05-25

source: Ensembl Release 99
stated in qid: Q83867711

wikidata id: Q5383694
domain: protein
level: standard
html url: https://4ort.xyz/entity/epithelial-cell-adhesion-molecule
markdown url: https://4ort.xyz/entity/epithelial-cell-adhesion-molecule.md
facts url summary: https://4ort.xyz/entity/epithelial-cell-adhesion-molecule/facts.json
facts url standard: https://4ort.xyz/entity/epithelial-cell-adhesion-molecule/facts.json
facts url full: https://4ort.xyz/entity/epithelial-cell-adhesion-molecule/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-02T14:04:32.546134Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-04-10T23:23:54.717050+00:00Z