# Epidermal growth factor receptor

> mammalian protein found in Mus musculus

**Wikidata**: [Q21981692](https://www.wikidata.org/wiki/Q21981692)  
**Source**: https://4ort.xyz/entity/epidermal-growth-factor-receptor-q21981692


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q01279)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
5. [Gab1 is an integrator of cell death versus cell survival signals in oxidative stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01279&geneProductId=UniProtKB:Q01279)
7. [G-protein-coupled receptor-mediated activation of rap GTPases: characterization of a novel Galphai regulated pathway](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01279&geneProductId=UniProtKB:Q01279)
8. [Protein kinase C-alpha and protein kinase C-epsilon are required for Grb2-associated binder-1 tyrosine phosphorylation in response to platelet-derived growth factor](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01279&geneProductId=UniProtKB:Q01279)
9. [CEACAM1 modulates epidermal growth factor receptor--mediated cell proliferation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
10. [Lung Tumor Suppressor GPRC5A Binds EGFR and Restrains Its Effector Signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
11. [Regulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
12. [Inhibition of the leucine-rich repeat protein LINGO-1 enhances survival, structure, and function of dopaminergic neurons in Parkinson's disease models](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
13. [Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor (EGFR) but are not required for coupling to the mitogen-activated protein (MAP) kinase signaling cascade](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
14. [Suppressor of cytokine signaling (SOCS)-5 is a potential negative regulator of epidermal growth factor signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
15. [Local phosphatidylinositol 3,4,5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated PC12 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
16. [CAML is required for efficient EGF receptor recycling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
17. [Threshold-controlled ubiquitination of the EGFR directs receptor fate](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
18. [Engineered epidermal growth factor mutants with faster binding on-rates correlate with enhanced receptor activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
19. [Advanced glycation end product (AGE) receptor 1 suppresses cell oxidant stress and activation signaling via EGF receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
20. [EGF receptor is required for KRAS-induced pancreatic tumorigenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
21. [Expression of the epidermal growth factor receptor gene is regulated in mouse blastocysts during delayed implantation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01279&geneProductId=UniProtKB:Q01279)
22. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01279&geneProductId=UniProtKB:Q01279)
23. [Protein kinase C-alpha and protein kinase C-epsilon are required for Grb2-associated binder-1 tyrosine phosphorylation in response to platelet-derived growth factor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
24. [G-protein-coupled receptor-mediated activation of rap GTPases: characterization of a novel Galphai regulated pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
25. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
26. [Expression of the epidermal growth factor receptor gene is regulated in mouse blastocysts during delayed implantation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
27. [Presenilin modulates EGFR signaling and cell transformation by regulating the ubiquitin ligase Fbw7](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
28. [Furin is the primary in vivo convertase of angiopoietin-like 3 and endothelial lipase in hepatocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
29. [Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01279&geneProductId=UniProtKB:Q01279)
30. [Altering the Expression of Cell Surface β1,4-Galactosyltransferase Modulates Cell Growth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
31. [Ectodysplasin, a protein required for epithelial morphogenesis, is a novel TNF homologue and promotes cell-matrix adhesion](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01279&geneProductId=UniProtKB:Q01279)
32. [Epidermal growth factor receptor expression is abnormal in murine polycystic kidney](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
33. [Ectodysplasin, a protein required for epithelial morphogenesis, is a novel TNF homologue and promotes cell-matrix adhesion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
34. [Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
35. [Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
36. [The synovial sarcoma SYT-SSX2 oncogene remodels the cytoskeleton through activation of the ephrin pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
37. [MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
38. [Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01279&geneProductId=UniProtKB:Q01279)
39. [Mutation in Sos1 dominantly enhances a weak allele of the EGFR, demonstrating a requirement for Sos1 in EGFR signaling and development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
40. [Submandibular gland morphogenesis: stage-specific expression of TGF-alpha/EGF, IGF, TGF-beta, TNF, and IL-6 signal transduction in normal embryonic mice and the phenotypic effects of TGF-beta2, TGF-beta3, and EGF-r null mutations](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
41. [Importance of epidermal growth factor receptor signaling in establishment of adenomas and maintenance of carcinomas during intestinal tumorigenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
42. [Betacellulin stimulates growth of the mouse intestinal epithelium and increases adenoma multiplicity in Apc+/Min mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01279&geneProductId=UniProtKB:Q01279)
43. [Altering the Expression of Cell Surface β1,4-Galactosyltransferase Modulates Cell Growth](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01279&geneProductId=UniProtKB:Q01279)
44. [Calpain 2 Activated through N-Methyl-d-Aspartic Acid Receptor Signaling Cleaves CPEB3 and Abrogates CPEB3-Repressed Translation in Neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
45. [The epidermal growth factor receptor couples transforming growth factor-alpha, heparin-binding epidermal growth factor-like factor, and amphiregulin to Neu, ErbB-3, and ErbB-4](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
46. [Betacellulin stimulates growth of the mouse intestinal epithelium and increases adenoma multiplicity in Apc+/Min mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01279)
47. ensembl Release 106