# Epidermal growth factor receptor Dmel_CG10079

> protein found in Drosophila melanogaster

**Wikidata**: [Q29820703](https://www.wikidata.org/wiki/Q29820703)  
**Source**: https://4ort.xyz/entity/epidermal-growth-factor-receptor-dmel-cg10079


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P04412)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
5. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
6. [Mechanism of activation of the Drosophila EGF Receptor by the TGFalpha ligand Gurken during oogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
7. [Secreted Spitz triggers the DER signaling pathway and is a limiting component in embryonic ventral ectoderm determination.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
8. [EGF domain swap converts a Drosophila EGF receptor activator into an inhibitor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
9. [Inhibition of Drosophila EGF receptor activation by the secreted protein Argos.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
10. [The interaction between the Drosophila secreted protein argos and the epidermal growth factor receptor inhibits dimerization of the receptor and binding of secreted spitz to the receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
11. [An extracellular interactome of immunoglobulin and LRR proteins reveals receptor-ligand networks.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
12. [Structural Basis for Negative Cooperativity in Growth Factor Binding to an EGF Receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
13. [D-Cbl binding to Drk leads to dose-dependent down-regulation of EGFR signaling and increases receptor-ligand endocytosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
14. [Echinoid is essential for regulation of Egfr signaling and R8 formation during Drosophila eye development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
15. [Mechanism of inhibition of the Drosophila and mammalian EGF receptors by the transmembrane protein Kekkon 1.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
16. [Mapping organelle proteins and protein complexes in Drosophila melanogaster](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
17. [Sprouty, an intracellular inhibitor of Ras signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
18. [Regulators of endocytosis maintain localized receptor tyrosine kinase signaling in guided migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
19. [Specificity of Drosophila Cytonemes for Distinct Signaling Pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
20. [Phospholipid membrane composition affects EGF receptor and Notch signaling through effects on endocytosis during Drosophila development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
21. [A Hox complex activates and potentiates the Epidermal Growth Factor signaling pathway to specify Drosophila oenocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
22. [A microRNA mediates EGF receptor signaling and promotes photoreceptor differentiation in the Drosophila eye](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
23. [Identification of genes controlling malpighian tubule and other epithelial morphogenesis in Drosophila melanogaster.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
24. [Affecting Rhomboid-3 function causes a dilated heart in adult Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
25. [Role of the EGFR/Ras/Raf pathway in specification of photoreceptor cells in the Drosophila retina](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
26. [MAPK/ERK signaling regulates insulin sensitivity to control glucose metabolism in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
27. [Dissecting the roles of the Drosophila EGF receptor in eye development and MAP kinase activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
28. [Distinct roles for two receptor tyrosine kinases in epithelial branching morphogenesis in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
29. [Differential activity of Ras1 during patterning of the Drosophila dorsoventral axis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
30. [The sevenless signalling cassette mediates Drosophila EGF receptor function during epidermal development.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
31. [Argos transcription is induced by the Drosophila EGF receptor pathway to form an inhibitory feedback loop.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
32. [Rhomboid and Star facilitate presentation and processing of the Drosophila TGF-alpha homolog Spitz](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
33. [Guidance of cell migration by EGF receptor signaling during Drosophila oogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
34. [GTP exchange factor Vav regulates guided cell migration by coupling guidance receptor signalling to local Rac activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
35. [Dystroglycan down-regulation links EGF receptor signaling and anterior-posterior polarity formation in the Drosophila oocyte](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
36. [Hox-controlled reorganisation of intrasegmental patterning cues underlies Drosophila posterior spiracle organogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
37. [Cellular pathways acting along the germband and in the amnioserosa may participate in germband retraction of the Drosophila melanogaster embryo.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
38. [Novel interplay between JNK and Egfr signaling in Drosophila dorsal closure](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
39. [Modulation of morphogenesis by Egfr during dorsal closure in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
40. [Reciprocal interactions between neurons and glia are required for Drosophila peripheral nervous system development.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
41. [EGF receptor attenuates Dpp signaling and helps to distinguish the wing and leg cell fates in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
42. [Epithelial cell adhesion in the developing Drosophila retina is regulated by Atonal and the EGF receptor pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
43. [Egfr/Ras pathway mediates interactions between peripodial and disc proper cells in Drosophila wing discs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
44. [The Drosophila Arf GEF Steppke controls MAPK activation in EGFR signaling.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
45. [rhomboid and Star interact synergistically to promote EGFR/MAPK signaling during Drosophila wing vein development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
46. [Epidermal growth factor receptor and transforming growth factor-beta signaling contributes to variation for wing shape in Drosophila melanogaster](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
47. [Dual role for Drosophila epidermal growth factor receptor signaling in early wing disc development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
48. [Distalization of the Drosophila leg by graded EGF-receptor activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
49. [Dynamic EGFR-Ras signalling in Drosophila leg development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)
50. [Negative regulation of Egfr/Ras pathway by Ultrabithorax during haltere development in Drosophila.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04412)