# Ephrin A1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21156333](https://www.wikidata.org/wiki/Q21156333)  
**Source**: https://4ort.xyz/entity/ephrin-a1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P20827)
3. Q20641742
4. [EphA2 mediates ligand-dependent inhibition and ligand-independent promotion of cell migration and invasion via a reciprocal regulatory loop with Akt](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20827)
5. [Ligand recognition by A-class Eph receptors: crystal structures of the EphA2 ligand-binding domain and the EphA2/ephrin-A1 complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20827)
6. [NMR structure of a heterodimeric SAM:SAM complex: characterization and manipulation of EphA2 binding reveal new cellular functions of SHIP2.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20827)
7. [Architecture of Eph receptor clusters](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20827)
8. [The genes encoding the eph-related receptor tyrosine kinase ligands LERK-1 (EPLG1, Epl1), LERK-3 (EPLG3, Epl3), and LERK-4 (EPLG4, Epl4) are clustered on human chromosome 1 and mouse chromosome 3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20827)
9. [A novel immediate-early response gene of endothelium is induced by cytokines and encodes a secreted protein](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P20827)
10. [Characterization of a novel Eph receptor tyrosine kinase, EphA10, expressed in testis](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P20827)
11. [GOA](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P20827)
12. [A novel immediate-early response gene of endothelium is induced by cytokines and encodes a secreted protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20827)
13. [Characterization of a novel Eph receptor tyrosine kinase, EphA10, expressed in testis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20827)
14. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20827)
15. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20827)
16. [The genes encoding the eph-related receptor tyrosine kinase ligands LERK-1 (EPLG1, Epl1), LERK-3 (EPLG3, Epl3), and LERK-4 (EPLG4, Epl4) are clustered on human chromosome 1 and mouse chromosome 3](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P20827)
17. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P20827)
18. [Ligand-dependent activation of EphA4 signaling regulates the proteolysis of amyloid precursor protein through a Lyn-mediated pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20827)
19. [Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20827)
20. [Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P20827)
21. Ensembl Release 99
22. UMLS 2023