# Engrailed 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q21498562](https://www.wikidata.org/wiki/Q21498562)  
**Source**: https://4ort.xyz/entity/engrailed-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P09065)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P09065&geneProductId=UniProtKB:P09065)
6. [Specification of dopaminergic subsets involves interplay of En1 and Pitx3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065)
7. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065)
8. [Engrailed genes are cell-autonomously required to prevent apoptosis in mesencephalic dopaminergic neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065)
9. [The role of Nurr1 in the development of dopaminergic neurons and Parkinson's disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065)
10. [The mouse Engrailed-1 gene and ventral limb patterning](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065)
11. [Novel regulatory interactions revealed by studies of murine limb pattern in Wnt-7a and En-1 mutants](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065)
12. [Progressive loss of dopaminergic neurons in the ventral midbrain of adult mice heterozygote for Engrailed1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065)
13. [Engrailed genes control developmental fate of serotonergic and noradrenergic neurons in mid- and hindbrain in a gene dose-dependent manner](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065)
14. [Fate of midbrain dopaminergic neurons controlled by the engrailed genes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065)
15. [Engrailed-1 as a target of the Wnt-1 signalling pathway in vertebrate midbrain development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065)
16. [Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065)
17. [En1 and Wnt7a interact with Dkk1 during limb development in the mouse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065)
18. [Midbrain dopaminergic neurons: control of their cell fate by the engrailed transcription factors](http://www.ebi.ac.uk/QuickGO/annotations?protein=P09065&geneProductId=UniProtKB:P09065)
19. [Engrailed genes are cell-autonomously required to prevent apoptosis in mesencephalic dopaminergic neurons](http://www.ebi.ac.uk/QuickGO/annotations?protein=P09065&geneProductId=UniProtKB:P09065)
20. [Engrailed genes control developmental fate of serotonergic and noradrenergic neurons in mid- and hindbrain in a gene dose-dependent manner](http://www.ebi.ac.uk/QuickGO/annotations?protein=P09065&geneProductId=UniProtKB:P09065)
21. [Protease nexin-1 is expressed at the mouse met-/mesencephalic junction and FGF signaling regulates its promoter activity in primary met-/mesencephalic cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065)
22. [Midbrain dopaminergic neurons: control of their cell fate by the engrailed transcription factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065)
23. ensembl Release 106