# endothelin 1

> mammalian protein found in human, mouse, rat

**Wikidata**: [Q390566](https://www.wikidata.org/wiki/Q390566)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Endothelin_1)  
**Source**: https://4ort.xyz/entity/endothelin-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P05305)
3. IUPHAR/BPS Guide to PHARMACOLOGY
4. Q20641742
5. Freebase Data Dumps. 2013
6. [The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05305)
7. [Expression and biological effects of endothelin-1 in human gonadotropin-releasing hormone-secreting neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05305)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05305)
9. [Krüppel-like factor 15 regulates BMPER in endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05305)
10. [Cloning and functional expression of human cDNA for the ETB endothelin receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05305)
11. [Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05305)
12. [Effects of endothelin-1 on release of adrenomedullin and C-type natriuretic peptide from individual human vascular endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05305)
13. [Elevated endothelin-1 levels impair nitric oxide homeostasis through a PKC-dependent pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05305)
14. [Ursodeoxycholic acid reduces increased circulating endothelin 2 in primary biliary cirrhosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05305)
15. [Adenovirus-mediated overexpression of caveolin-3 inhibits rat cardiomyocyte hypertrophy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05305)
16. [Effect of adrenomedullin on the production of endothelin-1 and on its vasoconstrictor action in resistance arteries: evidence for a receptor-specific functional interaction in patients with heart failure](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05305)
17. [Functional and Autoradiographic Studies of Endothelin-1 and Endothelin-2 in Human Bronchi, Pulmonary Arteries, and Airway Parasympathetic Ganglia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05305)
18. [Characterization of endothelin receptors in the human umbilical artery and vein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05305)
19. [Endothelins induce CCR7 expression by breast tumor cells via endothelin receptor A and hypoxia-inducible factor-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05305)
20. [Mechanisms of endothelin 1-stimulated proliferation in colorectal cancer cell lines](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05305)
21. [The involvement of protein kinase G in stimulation of neutrophil migration by endothelins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05305)
22. [Endothelin converting enzyme (ECE) activity in human vascular smooth muscle](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05305)
23. [Prostaglandin Endoperoxide Synthase-2 Contributes to the Endothelin/Sarafotoxin-Induced Prostaglandin E2 Synthesis in Mouse Osteoblastic Cells (MC3T3-E1): Evidence for a Protein Tyrosine Kinase-Signaling Pathway and Involvement of Protein Kinase C*](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05305)
24. [Endothelin-1 potentiates human smooth muscle cell growth to PDGF: effects of ETA and ETB receptor blockade](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05305)
25. [Effects of endothelins on signal transduction and proliferation in human melanocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05305)
26. [Permissive role of nitric oxide in endothelin-induced migration of endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05305)
27. [The miR-19a/b family positively regulates cardiomyocyte hypertrophy by targeting atrogin-1 and MuRF-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05305)
28. [OpenAlex](https://docs.openalex.org/download-snapshot/snapshot-data-format)