# endoglin

> mammalian protein found in Homo sapiens

**Wikidata**: [Q3054016](https://www.wikidata.org/wiki/Q3054016)  
**Source**: https://4ort.xyz/entity/endoglin-q3054016


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P17813)
3. Q20641742
4. [Endoglin forms a heteromeric complex with the signaling receptors for transforming growth factor-beta](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17813)
5. [Extracellular and cytoplasmic domains of endoglin interact with the transforming growth factor-beta receptors I and II](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17813)
6. [Identification and expression of two forms of the human transforming growth factor-beta-binding protein endoglin with distinct cytoplasmic regions](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17813&geneProductId=UniProtKB:P17813)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17813&geneProductId=UniProtKB:P17813)
8. [Endoglin: An accessory component of the TGF-beta-binding receptor-complex with diagnostic, prognostic, and bioimmunotherapeutic potential in human malignancies](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17813)
9. [Endoglin expression in metastatic breast cancer cells enhances their invasive phenotype](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17813&geneProductId=UniProtKB:P17813)
10. [Biochemical characterization of the 44G4 antigen from the HOON pre-B leukemic cell line](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17813)
11. [Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17813)
12. [Structural Basis of the Human Endoglin-BMP9 Interaction: Insights into BMP Signaling and HHT1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17813)
13. [Endoglin mediates fibronectin/α5β1 integrin and TGF-β pathway crosstalk in endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17813)
14. [Critical role of endoglin in tumor cell plasticity of Ewing sarcoma and melanoma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17813)
15. [Interaction and functional interplay between endoglin and ALK-1, two components of the endothelial transforming growth factor-beta receptor complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17813)
16. [Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17813)
17. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17813)
18. [S-endoglin expression is induced in senescent endothelial cells and contributes to vascular pathology](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17813)
19. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17813&geneProductId=UniProtKB:P17813)
20. [Regulated expression on human macrophages of endoglin, an Arg-Gly-Asp-containing surface antigen](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17813)
21. [Endoglin (CD105) as a urinary and serum marker of prostate cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17813)
22. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17813)
23. [Severe intrauterine growth restriction pregnancies have increased placental endoglin levels: hypoxic regulation via transforming growth factor-beta 3](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17813&geneProductId=UniProtKB:P17813)
24. [S-endoglin expression is induced in senescent endothelial cells and contributes to vascular pathology](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17813&geneProductId=UniProtKB:P17813)
25. [Molecular characterization and in situ localization of murine endoglin reveal that it is a transforming growth factor-beta binding protein of endothelial and stromal cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17813)
26. [Extracellular and cytoplasmic domains of endoglin interact with the transforming growth factor-beta receptors I and II](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17813&geneProductId=UniProtKB:P17813)
27. [Endoglin: An accessory component of the TGF-beta-binding receptor-complex with diagnostic, prognostic, and bioimmunotherapeutic potential in human malignancies](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17813&geneProductId=UniProtKB:P17813)
28. [Endoglin, a TGF-beta binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17813)
29. [Endoglin phosphorylation by ALK2 contributes to the regulation of prostate cancer cell migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17813)
30. [Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17813)
31. [miR‐342‐5p Is a Notch Downstream Molecule and Regulates Multiple Angiogenic Pathways Including Notch, Vascular Endothelial Growth Factor and Transforming Growth Factor β Signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17813)
32. Ensembl Release 99
33. UMLS 2023