# Embryonic ectoderm development

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21097479](https://www.wikidata.org/wiki/Q21097479)  
**Source**: https://4ort.xyz/entity/embryonic-ectoderm-development-q21097479


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O75530)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530)
5. [Mutations in genes encoding polycomb repressive complex 2 subunits cause Weaver syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530)
6. [Corepressor Protein CDYL Functions as a Molecular Bridge between Polycomb Repressor Complex 2 and Repressive Chromatin Mark Trimethylated Histone Lysine 27](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530)
7. [Role of the polycomb repressive complex 2 in acute promyelocytic leukemia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530)
8. [Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530)
9. [CRL4B catalyzes H2AK119 monoubiquitination and coordinates with PRC2 to promote tumorigenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530)
10. [Deconstruction of the SS18-SSX fusion oncoprotein complex: insights into disease etiology and therapeutics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530)
11. [Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG Islands](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530)
12. [The Polycomb group protein EZH2 directly controls DNA methylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530)
13. [CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530)
14. [ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530)
15. [A human interactome in three quantitative dimensions organized by stoichiometries and abundances](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530)
16. [A High-Density Map for Navigating the Human Polycomb Complexome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530)
17. [The Polycomb group protein EED couples TNF receptor 1 to neutral sphingomyelinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530)
18. [JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530)
19. [Role for the MOV10 RNA helicase in polycomb-mediated repression of the INK4a tumor suppressor.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530)
20. [Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530)
21. [The Drosophila Polycomb Group proteins ESC and E(Z) are present in a complex containing the histone-binding protein p55 and the histone deacetylase RPD3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530)
22. [Mutations in genes encoding polycomb repressive complex 2 subunits cause Weaver syndrome](http://www.ebi.ac.uk/QuickGO/annotations?protein=O75530&geneProductId=UniProtKB:O75530)
23. [Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity](http://www.ebi.ac.uk/QuickGO/annotations?protein=O75530&geneProductId=UniProtKB:O75530)
24. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530)
25. [Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530)
26. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O75530&geneProductId=UniProtKB:O75530)
27. [Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity](http://www.ebi.ac.uk/QuickGO/annotations?protein=O75530&geneProductId=UniProtKB:O75530)
28. [An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting](http://www.ebi.ac.uk/QuickGO/annotations?protein=O75530&geneProductId=UniProtKB:O75530)
29. [JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=O75530&geneProductId=UniProtKB:O75530)
30. [Characterization of Interactions between the Mammalian Polycomb-Group Proteins Enx1/EZH2 and EED Suggests the Existence of Different Mammalian Polycomb-Group Protein Complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530)
31. [An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530)
32. [Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75530)
33. Ensembl Release 99