# Ectonucleotide pyrophosphatase/phosphodiesterase 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21110158](https://www.wikidata.org/wiki/Q21110158)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Ectonucleotide_pyrophosphatase/phosphodiesterase_1)  
**Source**: https://4ort.xyz/entity/ectonucleotide-pyrophosphatase-phosphodiesterase-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P22413)
3. Q20641742
4. [Hydrolysis of 2'3'-cGAMP by ENPP1 and design of nonhydrolyzable analogs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22413)
5. [Membrane glycoprotein PC-1 and insulin resistance in non-insulin-dependent diabetes mellitus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22413)
6. [Differential mechanisms of inorganic pyrophosphate production by plasma cell membrane glycoprotein-1 and B10 in chondrocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22413)
7. [PC-1 nucleoside triphosphate pyrophosphohydrolase deficiency in idiopathic infantile arterial calcification](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22413)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22413)
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22413&geneProductId=UniProtKB:P22413)
10. [One of two chondrocyte‐expressed isoforms of cartilage intermediate‐layer protein functions as an insulin‐like growth factor 1 antagonist](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22413&geneProductId=UniProtKB:P22413)
11. [ENPP1 Mutation Causes Recessive Cole Disease by Altering Melanogenesis.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22413)
12. [The Q allele variant (GLN121) of membrane glycoprotein PC-1 interacts with the insulin receptor and inhibits insulin signaling more effectively than the common K allele variant (LYS121)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22413)
13. [Effects of Different Variants in the ENPP1 Gene on the Functional Properties of Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22413&geneProductId=UniProtKB:P22413)
14. [Characterization of human phosphodiesterase 12 and identification of a novel 2'-5' oligoadenylate nuclease - The ectonucleotide pyrophosphatase/phosphodiesterase 1.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22413)
15. [Effects of Different Variants in the ENPP1 Gene on the Functional Properties of Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22413)
16. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22413)
17. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22413&geneProductId=UniProtKB:P22413)
18. [One of two chondrocyte‐expressed isoforms of cartilage intermediate‐layer protein functions as an insulin‐like growth factor 1 antagonist](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22413)
19. [Molecular cloning of cDNAs for human fibroblast nucleotide pyrophosphatase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22413)
20. [Differential mechanisms of inorganic pyrophosphate production by plasma cell membrane glycoprotein-1 and B10 in chondrocytes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22413&geneProductId=UniProtKB:P22413)
21. [Integral and associated lysosomal membrane proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22413&geneProductId=UniProtKB:P22413)
22. [Ecto‐phosphodiesterase/pyrophosphatase of lymphocytes and non‐lymphoid cells: structure and function of the PC‐1 family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22413)
23. [Integral and associated lysosomal membrane proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22413)
24. [Role of ENPP1 on adipocyte maturation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22413&geneProductId=UniProtKB:P22413)
25. [Role of ENPP1 on adipocyte maturation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22413)
26. ensembl Release 93