# Early growth response 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q14864827](https://www.wikidata.org/wiki/Q14864827)  
**Source**: https://4ort.xyz/entity/early-growth-response-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P08046)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046)
5. [Oxygen deprivation triggers upregulation of early growth response-1 by the receptor for advanced glycation end products](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046)
6. [Differential Regulation of Early Growth Response Gene-1 Expression by Insulin and Glucose in Vascular Endothelial Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046)
7. [Phosphorylation and acetylation of histone H3 and autoregulation by early growth response 1 mediate interleukin 1beta induction of early growth response 1 transcription](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08046&geneProductId=UniProtKB:P08046)
8. [A novel repression module, an extensive activation domain, and a bipartite nuclear localization signal defined in the immediate-early transcription factor Egr-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046)
9. [Early growth response 1 acts as a tumor suppressor in vivo and in vitro via regulation of p53](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08046&geneProductId=UniProtKB:P08046)
11. [Early growth response 1 acts as a tumor suppressor in vivo and in vitro via regulation of p53](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08046&geneProductId=UniProtKB:P08046)
12. [A novel repression module, an extensive activation domain, and a bipartite nuclear localization signal defined in the immediate-early transcription factor Egr-1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08046&geneProductId=UniProtKB:P08046)
13. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08046&geneProductId=UniProtKB:P08046)
14. [Phosphorylation and acetylation of histone H3 and autoregulation by early growth response 1 mediate interleukin 1beta induction of early growth response 1 transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046)
15. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046)
16. [Egr-1, a master switch coordinating upregulation of divergent gene families underlying ischemic stress](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08046&geneProductId=UniProtKB:P08046)
17. [Differential Regulation of Early Growth Response Gene-1 Expression by Insulin and Glucose in Vascular Endothelial Cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08046&geneProductId=UniProtKB:P08046)
18. [Oxygen deprivation triggers upregulation of early growth response-1 by the receptor for advanced glycation end products](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08046&geneProductId=UniProtKB:P08046)
19. [NAB2, a corepressor of NGFI-A (Egr-1) and Krox20, is induced by proliferative and differentiative stimuli](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08046&geneProductId=UniProtKB:P08046)
20. [Egr-1, a master switch coordinating upregulation of divergent gene families underlying ischemic stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046)
21. [NAB2, a corepressor of NGFI-A (Egr-1) and Krox20, is induced by proliferative and differentiative stimuli](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046)
22. [Domain-specific c-Myc ubiquitylation controls c-Myc transcriptional and apoptotic activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046)
23. [Regulation of GATA-3 expression during CD4 lineage differentiation.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046)
24. [Thymocyte development in early growth response gene 1-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08046&geneProductId=UniProtKB:P08046)
25. [Temporal-spatial expression and transcriptional regulation of alpha7 nicotinic acetylcholine receptor by thyroid transcription factor-1 and early growth response factor-1 during murine lung development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046)
26. [Molecular mechanisms of cell and tissue interactions during early tooth development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046)
27. [EGR1 regulates hepatic clock gene amplitude by activating Per1 transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046)
28. [Phosphorylation of protein phosphatase 1 by cyclin-dependent protein kinase 5 during nerve growth factor-induced PC12 cell differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046)
29. [Repression of Pax-2 by WT1 during normal kidney development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046)
30. [Thymocyte development in early growth response gene 1-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046)
31. [PTEN regulation by Akt-EGR1-ARF-PTEN axis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046)
32. [Analysis of early C2C12 myogenesis identifies stably and differentially expressed transcriptional regulators whose knock-down inhibits myoblast differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046)
33. [Negative regulation of the Wnt signal by MM-1 through inhibiting expression of the wnt4 gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046)
34. [Luteinizing hormone deficiency and female infertility in mice lacking the transcription factor NGFI-A (Egr-1)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046)
35. [Mice Lacking EGR1 Have Impaired Clock Gene (BMAL1) Oscillation, Locomotor Activity, and Body Temperature.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046)
36. ensembl Release 106
37. [Identifiers.org](https://registry.identifiers.org/registry/uniprot)