# Early growth response 1

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28557378](https://www.wikidata.org/wiki/Q28557378)  
**Source**: https://4ort.xyz/entity/early-growth-response-1-q28557378


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P08154)
3. Q20641742
4. [Co-operative interactions between NFAT (nuclear factor of activated T cells) c1 and the zinc finger transcription factors Sp1/Sp3 and Egr-1 regulate MT1-MMP (membrane type 1 matrix metalloproteinase) transcription by glomerular mesangial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
5. [Signal transduction of pregnenolone sulfate in insulinoma cells: activation of Egr-1 expression involving TRPM3, voltage-gated calcium channels, ERK, and ternary complex factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
6. [Egr-1 transactivates Bim gene expression to promote neuronal apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
7. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
8. [Early growth response gene-1 regulates the expression of the rat luteinizing hormone receptor gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
10. [Sequential increase in Egr-1 and AP-1 DNA binding activity in the dentate gyrus following the induction of long-term potentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
11. [Inhibition of gluconeogenesis through transcriptional activation of EGR1 and DUSP4 by AMP-activated kinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
12. [Effect of cysteamine on redox-sensitive thiol-containing proteins in the duodenal mucosa](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
13. [Distinctive features of Egr transcription factor regulation and DNA binding activity in CA1 of the hippocampus in synaptic plasticity and consolidation and reconsolidation of fear memory](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
14. [A dominant negative Egr inhibitor blocks nerve growth factor-induced neurite outgrowth by suppressing c-Jun activation: role of an Egr/c-Jun complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
15. [Early growth response‐1 transcription factor promotes hepatic fibrosis and steatosis in long‐term ethanol‐fed Long‐Evans rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
16. [Transcription factor Egr-1 regulates glomerular mesangial cell proliferation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
17. [Localization of the protein product of the immediate early growth response gene, Egr-1, in the kidney after ischemia and reperfusion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
18. [Chronic methamphetamine exposure suppresses the striatal expression of members of multiple families of immediate early genes (IEGs) in the rat: normalization by an acute methamphetamine injection](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
19. [Local and descending circuits regulate long-term potentiation and zif268 expression in spinal neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
20. [Induction of hippocampal long-term potentiation during waking leads to increased extrahippocampal zif-268 expression during ensuing rapid-eye-movement sleep](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
21. [Maintenance of long-term memory storage is dependent on late posttraining Egr-1 expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
22. [A Circadian Clock Entrained by Melatonin Is Ticking in the Rat Fetal Adrenal](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
23. [<i>N</i>-n-butyl Haloperidol Iodide Protects Cardiac Microvascular Endothelial Cells From Hypoxia/Reoxygenation Injury by Down-Regulating Egr-1 Expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
24. [Apelin-13-induced proliferation and migration induced of rat vascular smooth muscle cells is mediated by the upregulation of Egr-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
25. [Dietary Fructooligosaccharides and Wheat Bran Elicit Specific and Dose-Dependent Gene Expression Profiles in the Proximal Colon Epithelia of Healthy Fischer 344 Rats1–3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
26. [Egr-1 induction in rat granulosa cells by follicle-stimulating hormone and luteinizing hormone: combinatorial regulation by transcription factors cyclic adenosine 3',5'-monophosphate regulatory element binding protein, serum response factor, sp1, an](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
27. [Insulin-regulated expression of Egr-1 and Krox20: dependence on ERK1/2 and interaction with p38 and PI3-kinase pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
28. [Carbon monoxide rescues ischemic lungs by interrupting MAPK-driven expression of early growth response 1 gene and its downstream target genes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
29. [Time-dependent expression and distribution of Egr-1 during skeletal muscle wound healing in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
30. [Repeated electroconvulsive seizure treatment in rats reduces inducibility of early growth response genes and hyperactivity in response to cocaine administration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
31. [ERK1/2 and Egr-1 contribute to increased TNF-α production in rat Kupffer cells after chronic ethanol feeding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
32. [Imipramine activates glial cell line-derived neurotrophic factor via early growth response gene 1 in astrocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
33. [Identification of a gene regulatory network necessary for the initiation of oligodendrocyte differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
34. [Stretch-activated signaling pathways responsible for early response gene expression in fetal lung epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
35. [Berberine suppresses MEK/ERK-dependent Egr-1 signaling pathway and inhibits vascular smooth muscle cell regrowth after in vitro mechanical injury](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
36. [Early Growth Response 1 (Egr-1) Regulates Phosphorylation of Microtubule-associated Protein Tau in Mammalian Brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
37. [Cyclosporine modulates the response to hypoxia-reoxygenation in pulmonary artery endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
38. [Mycophenolic acid inhibits the autocrine PDGF-B synthesis and PDGF-BB-induced mRNA expression of Egr-1 in rat mesangial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
39. [Expression of nuclear proto-oncogenes in isoproterenol-induced cardiac hypertrophy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08154)
40. ensembl Release 106