# E1A binding protein p300

> mammalian protein found in Homo sapiens

**Wikidata**: [Q5323823](https://www.wikidata.org/wiki/Q5323823)  
**Source**: https://4ort.xyz/entity/e1a-binding-protein-p300


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q09472)
4. Q20641742
5. [Functional architecture of atrophins](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
6. [A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
7. [A novel zinc finger protein TReP-132 interacts with CBP/p300 to regulate human CYP11A1 gene expression](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
8. [Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
9. [Reactive Oxygen Species (ROS) Mediate p300-dependent STAT1 Protein Interaction with Peroxisome Proliferator-activated Receptor (PPAR)-γ in CD36 Protein Expression and Foam Cell Formation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
11. [HLA-B-associated transcript 3 (Bat3)/Scythe is essential for p300-mediated acetylation of p53](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
12. [ICAT inhibits beta-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300 using independent structural modules](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
13. [MED25 is distinct from TRAP220/MED1 in cooperating with CBP for retinoid receptor activation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
14. [Intracellular crotonyl-CoA stimulates transcription through p300-catalyzed histone crotonylation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
15. [CBP and p300 acetylate PCNA to link its degradation with nucleotide excision repair synthesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
16. [A novel cofactor for p300 that regulates the p53 response](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
17. [Selective coactivation of estrogen-dependent transcription by CITED1 CBP/p300-binding protein](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
18. [Dendrite development regulated by CREST, a calcium-regulated transcriptional activator](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
19. [The coactivator p300 directly acetylates the forkhead transcription factor Foxo1 and stimulates Foxo1-induced transcription](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
20. [Histone acetyltransferase-dependent chromatin remodeling and the vascular clock](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
21. [Orphan nuclear receptor small heterodimer partner, a novel corepressor for a basic helix-loop-helix transcription factor BETA2/neuroD](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
22. [The MSG1 non-DNA-binding transactivator binds to the p300/CBP coactivators, enhancing their functional link to the Smad transcription factors](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
23. [Scaffold/matrix attachment region elements interact with a p300-scaffold attachment factor A complex and are bound by acetylated nucleosomes.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
24. [Induction of SOX4 by DNA damage is critical for p53 stabilization and function](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
25. [Two ZNF509 (ZBTB49) isoforms induce cell-cycle arrest by activating transcription of p21/CDKN1A and RB upon exposure to genotoxic stress](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
26. [p29ING4 and p28ING5 bind to p53 and p300, and enhance p53 activity](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
27. [Regulation of E2A activities by histone acetyltransferases in B lymphocyte development](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
28. [Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
29. [Differential regulation of estrogen receptor α expression in breast cancer cells by metastasis-associated protein 1](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
30. [Modification of ASC1 by UFM1 is crucial for ERα transactivation and breast cancer development](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
31. [P300/CBP acts as a coactivator to cartilage homeoprotein-1 (Cart1), paired-like homeoprotein, through acetylation of the conserved lysine residue adjacent to the homeodomain](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
32. [Binding and modulation of p53 by p300/CBP coactivators](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
33. [Cited1 is a bifunctional transcriptional cofactor that regulates early nephronic patterning](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
34. [Foxp3 represses retroviral transcription by targeting both NF-kappaB and CREB pathways](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
35. [Regulation of human flap endonuclease-1 activity by acetylation through the transcriptional coactivator p300](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
36. [Acetylation of Dna2 endonuclease/helicase and flap endonuclease 1 by p300 promotes DNA stability by creating long flap intermediates](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
37. [Positive and negative modulation of the transcriptional activity of the ETS factor ESE-1 through interaction with p300, CREB-binding protein, and Ku 70/86](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
38. [Kruppel-like factor 15 is critical for vascular inflammation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
39. [Interferon regulatory factor 1 binding to p300 stimulates DNA-dependent acetylation of p53](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
40. [The transcriptional activity of CITED1 is regulated by phosphorylation in a cell cycle-dependent manner](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
41. [Acetylation of Sirt2 by p300 attenuates its deacetylase activity](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
42. [BRD7 is a candidate tumour suppressor gene required for p53 function](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
43. [Lyl1 interacts with CREB1 and alters expression of CREB1 target genes](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
44. [Physical and functional interactions among AP-2 transcription factors, p300/CREB-binding protein, and CITED2](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
45. [Critical and functional regulation of CHOP (C/EBP homologous protein) through the N-terminal portion](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
46. [The Smad3 linker region contains a transcriptional activation domain](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
47. [A novel Rb- and p300-binding protein inhibits transactivation by MyoD](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
48. [PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
49. [AIB1 is a conduit for kinase-mediated growth factor signaling to the estrogen receptor](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)
50. [SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09472&geneProductId=UniProtKB:Q09472)