# Dyskerin pseudouridine synthase 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21131972](https://www.wikidata.org/wiki/Q21131972)  
**Source**: https://4ort.xyz/entity/dyskerin-pseudouridine-synthase-1-q21131972


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O60832)
3. Q20641742
4. [Differential regulation of telomerase activity by six telomerase subunits](http://www.ebi.ac.uk/QuickGO/annotations?protein=O60832&geneProductId=UniProtKB:O60832)
5. [HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment](http://www.ebi.ac.uk/QuickGO/annotations?protein=O60832&geneProductId=UniProtKB:O60832)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O60832&geneProductId=UniProtKB:O60832)
7. [Purification of human telomerase complexes identifies factors involved in telomerase biogenesis and telomere length regulation](http://www.ebi.ac.uk/QuickGO/annotations?protein=O60832&geneProductId=UniProtKB:O60832)
8. [hNaf1 is required for accumulation of human box H/ACA snoRNPs, scaRNPs, and telomerase](http://www.ebi.ac.uk/QuickGO/annotations?protein=O60832&geneProductId=UniProtKB:O60832)
9. [SHQ1 is required prior to NAF1 for assembly of H/ACA small nucleolar and telomerase RNPs](http://www.ebi.ac.uk/QuickGO/annotations?protein=O60832&geneProductId=UniProtKB:O60832)
10. [A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=O60832&geneProductId=UniProtKB:O60832)
11. [Stepwise RNP assembly at the site of H/ACA RNA transcription in human cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=O60832&geneProductId=UniProtKB:O60832)
12. [A human interactome in three quantitative dimensions organized by stoichiometries and abundances](http://www.ebi.ac.uk/QuickGO/annotations?protein=O60832&geneProductId=UniProtKB:O60832)
13. [Identification of ATPases pontin and reptin as telomerase components essential for holoenzyme assembly](http://www.ebi.ac.uk/QuickGO/annotations?protein=O60832&geneProductId=UniProtKB:O60832)
14. [Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex](http://www.ebi.ac.uk/QuickGO/annotations?protein=O60832&geneProductId=UniProtKB:O60832)
15. [An enhanced H/ACA RNP assembly mechanism for human telomerase RNA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O60832&geneProductId=UniProtKB:O60832)
16. [Specificity and Stoichiometry of Subunit Interactions in the Human Telomerase Holoenzyme Assembled In Vivo](http://www.ebi.ac.uk/QuickGO/annotations?protein=O60832&geneProductId=UniProtKB:O60832)
17. [Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects](http://www.ebi.ac.uk/QuickGO/annotations?protein=O60832&geneProductId=UniProtKB:O60832)
18. [A telomerase component is defective in the human disease dyskeratosis congenita](http://www.ebi.ac.uk/QuickGO/annotations?protein=O60832&geneProductId=UniProtKB:O60832)
19. [Insights into RNA biology from an atlas of mammalian mRNA-binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=O60832&geneProductId=UniProtKB:O60832)
20. [Dyskerin localizes to the nucleolus and its mislocalization is unlikely to play a role in the pathogenesis of dyskeratosis congenita](http://www.ebi.ac.uk/QuickGO/annotations?protein=O60832&geneProductId=UniProtKB:O60832)
21. [X-linked dyskeratosis congenita is caused by mutations in a highly conserved gene with putative nucleolar functions](http://www.ebi.ac.uk/QuickGO/annotations?protein=O60832&geneProductId=UniProtKB:O60832)
22. [Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1](http://www.ebi.ac.uk/QuickGO/annotations?protein=O60832&geneProductId=UniProtKB:O60832)
23. Ensembl Release 99